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Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia.
Liu Y, Li Q, Alikarami F, Barrett DR, Mahdavi L, Li H, Tang S, Khan TA, Michino M, Hill C, Song L, Yang L, Li Y, Pokharel SP, Stamford AW, Liverton N, Renzetti LM, Taylor S, Watt GF, Ladduwahetty T, Kargman S, Meinke PT, Foley MA, Shi J, Li H, Carroll M, Chen CW, Gardini A, Maillard I, Huggins DJ, Bernt KM, Wan L. Liu Y, et al. Among authors: gardini a. Cancer Discov. 2022 Nov 2;12(11):2684-2709. doi: 10.1158/2159-8290.CD-21-1307. Cancer Discov. 2022. PMID: 36053276 Free PMC article.
Targeted Enhancer Activation by a Subunit of the Integrator Complex.
Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A. Barbieri E, et al. Among authors: gardini a. Mol Cell. 2018 Jul 5;71(1):103-116.e7. doi: 10.1016/j.molcel.2018.05.031. Epub 2018 Jun 28. Mol Cell. 2018. PMID: 30008316 Free PMC article.
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Carrer A, Trefely S, Zhao S, Campbell SL, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, Snyder NW, Stanger BZ, Wellen KE. Carrer A, et al. Among authors: gardini a. Cancer Discov. 2019 Mar;9(3):416-435. doi: 10.1158/2159-8290.CD-18-0567. Epub 2019 Jan 9. Cancer Discov. 2019. PMID: 30626590 Free PMC article.
Rapid and Scalable Profiling of Nascent RNA with fastGRO.
Barbieri E, Hill C, Quesnel-Vallières M, Zucco AJ, Barash Y, Gardini A. Barbieri E, et al. Among authors: gardini a. Cell Rep. 2020 Nov 10;33(6):108373. doi: 10.1016/j.celrep.2020.108373. Cell Rep. 2020. PMID: 33176136 Free PMC article.
Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression.
Porazzi P, Petruk S, Pagliaroli L, De Dominici M, Deming D 2nd, Puccetti MV, Kushinsky S, Kumar G, Minieri V, Barbieri E, Deliard S, Grande A, Trizzino M, Gardini A, Canaani E, Palmisiano N, Porcu P, Ertel A, Fortina P, Eischen CM, Mazo A, Calabretta B. Porazzi P, et al. Among authors: gardini a. Cancer Res. 2022 Feb 1;82(3):458-471. doi: 10.1158/0008-5472.CAN-21-1297. Epub 2021 Dec 13. Cancer Res. 2022. PMID: 34903608 Free PMC article.
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R. Yokoyama Y, et al. Among authors: gardini a. Cancer Res. 2016 Nov 1;76(21):6320-6330. doi: 10.1158/0008-5472.CAN-16-0854. Cancer Res. 2016. PMID: 27803105 Free PMC article.
G-quadruplexes associated with R-loops promote CTCF binding.
Wulfridge P, Yan Q, Rell N, Doherty J, Jacobson S, Offley S, Deliard S, Feng K, Phillips-Cremins JE, Gardini A, Sarma K. Wulfridge P, et al. Among authors: gardini a. Mol Cell. 2023 Sep 7;83(17):3064-3079.e5. doi: 10.1016/j.molcel.2023.07.009. Epub 2023 Aug 7. Mol Cell. 2023. PMID: 37552993
Long noncoding RNAs with enhancer-like function in human cells.
Ørom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, Lai F, Zytnicki M, Notredame C, Huang Q, Guigo R, Shiekhattar R. Ørom UA, et al. Among authors: gardini a. Cell. 2010 Oct 1;143(1):46-58. doi: 10.1016/j.cell.2010.09.001. Cell. 2010. PMID: 20887892 Free PMC article.
143 results