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Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression.
Porazzi P, Petruk S, Pagliaroli L, De Dominici M, Deming D 2nd, Puccetti MV, Kushinsky S, Kumar G, Minieri V, Barbieri E, Deliard S, Grande A, Trizzino M, Gardini A, Canaani E, Palmisiano N, Porcu P, Ertel A, Fortina P, Eischen CM, Mazo A, Calabretta B. Porazzi P, et al. Among authors: gardini a. Cancer Res. 2022 Feb 1;82(3):458-471. doi: 10.1158/0008-5472.CAN-21-1297. Epub 2021 Dec 13. Cancer Res. 2022. PMID: 34903608 Free PMC article.
A combinatorial approach to uncover an additional Integrator subunit.
Offley SR, Pfleiderer MM, Zucco A, Fraudeau A, Welsh SA, Razew M, Galej WP, Gardini A. Offley SR, et al. Among authors: gardini a. Cell Rep. 2023 Mar 28;42(3):112244. doi: 10.1016/j.celrep.2023.112244. Epub 2023 Mar 14. Cell Rep. 2023. PMID: 36920904 Free PMC article.
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R. Yokoyama Y, et al. Among authors: gardini a. Cancer Res. 2016 Nov 1;76(21):6320-6330. doi: 10.1158/0008-5472.CAN-16-0854. Cancer Res. 2016. PMID: 27803105 Free PMC article.
Targeted Enhancer Activation by a Subunit of the Integrator Complex.
Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A. Barbieri E, et al. Among authors: gardini a. Mol Cell. 2018 Jul 5;71(1):103-116.e7. doi: 10.1016/j.molcel.2018.05.031. Epub 2018 Jun 28. Mol Cell. 2018. PMID: 30008316 Free PMC article.
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Carrer A, Trefely S, Zhao S, Campbell SL, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, Snyder NW, Stanger BZ, Wellen KE. Carrer A, et al. Among authors: gardini a. Cancer Discov. 2019 Mar;9(3):416-435. doi: 10.1158/2159-8290.CD-18-0567. Epub 2019 Jan 9. Cancer Discov. 2019. PMID: 30626590 Free PMC article.
Rapid and Scalable Profiling of Nascent RNA with fastGRO.
Barbieri E, Hill C, Quesnel-Vallières M, Zucco AJ, Barash Y, Gardini A. Barbieri E, et al. Among authors: gardini a. Cell Rep. 2020 Nov 10;33(6):108373. doi: 10.1016/j.celrep.2020.108373. Cell Rep. 2020. PMID: 33176136 Free PMC article.
EGR1 is a gatekeeper of inflammatory enhancers in human macrophages.
Trizzino M, Zucco A, Deliard S, Wang F, Barbieri E, Veglia F, Gabrilovich D, Gardini A. Trizzino M, et al. Among authors: gardini a. Sci Adv. 2021 Jan 13;7(3):eaaz8836. doi: 10.1126/sciadv.aaz8836. Print 2021 Jan. Sci Adv. 2021. PMID: 33523892 Free PMC article.
G-quadruplexes associated with R-loops promote CTCF binding.
Wulfridge P, Yan Q, Rell N, Doherty J, Jacobson S, Offley S, Deliard S, Feng K, Phillips-Cremins JE, Gardini A, Sarma K. Wulfridge P, et al. Among authors: gardini a. Mol Cell. 2023 Sep 7;83(17):3064-3079.e5. doi: 10.1016/j.molcel.2023.07.009. Epub 2023 Aug 7. Mol Cell. 2023. PMID: 37552993
143 results