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Sofosbuvir shows a protective effect against vertical transmission of Zika virus and the associated congenital syndrome in rhesus monkeys.
Gardinali NR, Marchevsky RS, Oliveira JM, Pelajo-Machado M, Kugelmeier T, Castro MP, Silva ACA, Pinto DP, Fonseca LB, Vilhena LS, Pereira HM, Lima SMB, Miranda EH, Trindade GF, Linhares JHR, Silva SA, Melgaço JG, Alves AMB, Moran J, Silva MCC, Soares-Bezerra RJ, Soriano A, Bentes GA, Bottino FO, Salvador Castro Faria SB, Nudelman RF, Lopes CAA, Perea JAS, Sarges K, Andrade MCR, Motta MCVA, Freire MS, Souza TML, Schmidt-Chanasit J, Pinto MA. Gardinali NR, et al. Antiviral Res. 2020 Oct;182:104859. doi: 10.1016/j.antiviral.2020.104859. Epub 2020 Jul 7. Antiviral Res. 2020. PMID: 32649965
Cynomolgus monkeys are successfully and persistently infected with hepatitis E virus genotype 3 (HEV-3) after long-term immunosuppressive therapy.
Gardinali NR, Guimarães JR, Melgaço JG, Kevorkian YB, Bottino FO, Vieira YR, da Silva AC, Pinto DP, da Fonseca LB, Vilhena LS, Uiechi E, da Silva MC, Moran J, Marchevsky RS, Cruz OG, Otonel RA, Alfieri AA, de Oliveira JM, Gaspar AM, Pinto MA. Gardinali NR, et al. PLoS One. 2017 Mar 22;12(3):e0174070. doi: 10.1371/journal.pone.0174070. eCollection 2017. PLoS One. 2017. PMID: 28328941 Free PMC article.
Serological and virological survey of hepatitis E virus (HEV) in animal reservoirs from Uruguay reveals elevated prevalences and a very close phylogenetic relationship between swine and human strains.
Mirazo S, Gardinali NR, Cecilia D, Verger L, Ottonelli F, Ramos N, Castro G, Pinto MA, Ré V, Pisano B, Lozano A, de Oliveira JM, Arbiza J. Mirazo S, et al. Among authors: gardinali nr. Vet Microbiol. 2018 Jan;213:21-27. doi: 10.1016/j.vetmic.2017.11.013. Epub 2017 Nov 14. Vet Microbiol. 2018. PMID: 29291999
Hepatitis E: Update on Prevention and Control.
Melgaço JG, Gardinali NR, de Mello VDM, Leal M, Lewis-Ximenez LL, Pinto MA. Melgaço JG, et al. Among authors: gardinali nr. Biomed Res Int. 2018 Jan 9;2018:5769201. doi: 10.1155/2018/5769201. eCollection 2018. Biomed Res Int. 2018. PMID: 29546064 Free PMC article. Review.
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