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Page 1
γδ T Lymphocytes in the Diagnosis of Human T Cell Receptor Immunodeficiencies.
Garcillán B, Marin AV, Jiménez-Reinoso A, Briones AC, Muñoz-Ruiz M, García-León MJ, Gil J, Allende LM, Martínez-Naves E, Toribio ML, Regueiro JR. Garcillán B, et al. Front Immunol. 2015 Jan 29;6:20. doi: 10.3389/fimmu.2015.00020. eCollection 2015. Front Immunol. 2015. PMID: 25688246 Free PMC article. Review. No abstract available.
Human CD3γ, but not CD3δ, haploinsufficiency differentially impairs γδ versus αβ surface TCR expression.
Muñoz-Ruiz M, Pérez-Flores V, Garcillán B, Guardo AC, Mazariegos MS, Takada H, Allende LM, Kilic SS, Sanal O, Roifman CM, López-Granados E, Recio MJ, Martínez-Naves E, Fernández-Malavé E, Regueiro JR. Muñoz-Ruiz M, et al. Among authors: garcillan b. BMC Immunol. 2013 Jan 21;14:3. doi: 10.1186/1471-2172-14-3. BMC Immunol. 2013. PMID: 23336327 Free PMC article.
Primary T-cell immunodeficiency with functional revertant somatic mosaicism in CD247.
Marin AV, Jiménez-Reinoso A, Briones AC, Muñoz-Ruiz M, Aydogmus C, Pasick LJ, Couso J, Mazariegos MS, Alvarez-Prado AF, Blázquez-Moreno A, Cipe FE, Haskologlu S, Dogu F, Morín M, Moreno-Pelayo MA, García-Sánchez F, Gil-Herrera J, Fernández-Malavé E, Reyburn HT, Ramiro AR, Ikinciogullari A, Recio MJ, Regueiro JR, Garcillán B. Marin AV, et al. Among authors: garcillan b. J Allergy Clin Immunol. 2017 Jan;139(1):347-349.e8. doi: 10.1016/j.jaci.2016.06.020. Epub 2016 Aug 21. J Allergy Clin Immunol. 2017. PMID: 27555457 No abstract available.
CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCRαβ Complex.
Garcillán B, Fuentes P, Marin AV, Megino RF, Chacon-Arguedas D, Mazariegos MS, Jiménez-Reinoso A, Muñoz-Ruiz M, Laborda RG, Cárdenas PP, Fernández-Malavé E, Toribio ML, Regueiro JR. Garcillán B, et al. Front Cell Dev Biol. 2021 Jun 25;9:608490. doi: 10.3389/fcell.2021.608490. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34249896 Free PMC article.
Natural killer cell hyporesponsiveness and impaired development in a CD247-deficient patient.
Valés-Gómez M, Esteso G, Aydogmus C, Blázquez-Moreno A, Marín AV, Briones AC, Garcillán B, García-Cuesta EM, López Cobo S, Haskologlu S, Moraru M, Cipe F, Dobbs K, Dogu F, Parolini S, Notarangelo LD, Vilches C, Recio MJ, Regueiro JR, Ikinciogullari A, Reyburn HT. Valés-Gómez M, et al. Among authors: garcillan b. J Allergy Clin Immunol. 2016 Mar;137(3):942-5.e4. doi: 10.1016/j.jaci.2015.07.051. Epub 2015 Nov 2. J Allergy Clin Immunol. 2016. PMID: 26542031 No abstract available.
The role of the different CD3γ domains in TCR expression and signaling.
Garcillán B, Megino RF, Herrero-Alonso M, Guardo AC, Perez-Flores V, Juraske C, Idstein V, Martin-Fernandez JM, Geisler C, Schamel WWA, Marin AV, Regueiro JR. Garcillán B, et al. Front Immunol. 2022 Sep 2;13:978658. doi: 10.3389/fimmu.2022.978658. eCollection 2022. Front Immunol. 2022. PMID: 36119034 Free PMC article.
The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.
Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA. Dopfer EP, et al. Among authors: garcillan b. Cell Rep. 2014 Jun 12;7(5):1704-1715. doi: 10.1016/j.celrep.2014.04.049. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857663 Free article.
A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ-Tγδ+B+NK+ human SCID.
Gil J, Busto EM, Garcillán B, Chean C, García-Rodríguez MC, Díaz-Alderete A, Navarro J, Reiné J, Mencía A, Gurbindo D, Beléndez C, Gordillo I, Duchniewicz M, Höhne K, García-Sánchez F, Fernández-Cruz E, López-Granados E, Schamel WW, Moreno-Pelayo MA, Recio MJ, Regueiro JR. Gil J, et al. Among authors: garcillan b. J Clin Invest. 2011 Oct;121(10):3872-6. doi: 10.1172/JCI44254. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926461 Free PMC article.
18 results