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Page 1
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
Zani F, Blagih J, Gruber T, Buck MD, Jones N, Hennequart M, Newell CL, Pilley SE, Soro-Barrio P, Kelly G, Legrave NM, Cheung EC, Gilmore IS, Gould AP, Garcia-Caceres C, Vousden KH. Zani F, et al. Among authors: garcia caceres c. Nature. 2023 Mar;615(7953):705-711. doi: 10.1038/s41586-023-05801-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922598 Free PMC article.
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.
Gruber T, Lechner F, Murat C, Contreras RE, Sanchez-Quant E, Miok V, Makris K, Le Thuc O, González-García I, García-Clave E, Althammer F, Krabichler Q, DeCamp LM, Jones RG, Lutter D, Williams RH, Pfluger PT, Müller TD, Woods SC, Pospisilik JA, Martinez-Jimenez CP, Tschöp MH, Grinevich V, García-Cáceres C. Gruber T, et al. Among authors: garcia caceres c. Cell Rep. 2023 Oct 31;42(10):113305. doi: 10.1016/j.celrep.2023.113305. Cell Rep. 2023. PMID: 37864798 Free PMC article.
Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.
Grandl G, Collden G, Feng J, Bhattacharya S, Klingelhuber F, Schomann L, Bilekova S, Ansarullah, Xu W, Far FF, Tost M, Gruber T, Bastidas-Ponce A, Zhang Q, Novikoff A, Liskiewicz A, Liskiewicz D, Garcia-Caceres C, Feuchtinger A, Tschöp MH, Krahmer N, Lickert H, Müller TD. Grandl G, et al. Among authors: garcia caceres c. Nat Metab. 2024 Mar;6(3):448-457. doi: 10.1038/s42255-024-00991-3. Epub 2024 Feb 28. Nat Metab. 2024. PMID: 38418586 Free PMC article.
Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner.
González-Vila A, Luengo-Mateos M, Silveira-Loureiro M, Garrido-Gil P, Ohinska N, González-Domínguez M, Labandeira-García JL, García-Cáceres C, López M, Barca-Mayo O. González-Vila A, et al. Among authors: garcia caceres c. Nat Commun. 2023 Dec 9;14(1):8175. doi: 10.1038/s41467-023-44039-8. Nat Commun. 2023. PMID: 38071352 Free PMC article.
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.
Liskiewicz D, Zhang Q, Barthem CS, Jastroch M, Liskiewicz A, Khajavi N, Grandl G, Coupland C, Kleinert M, Garcia-Caceres C, Novikoff A, Maity G, Boehm U, Tschöp MH, Müller TD. Liskiewicz D, et al. Among authors: garcia caceres c. Mol Metab. 2023 Jun;72:101714. doi: 10.1016/j.molmet.2023.101714. Epub 2023 Mar 24. Mol Metab. 2023. PMID: 36966947 Free PMC article.
The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.
Giroud M, Kotschi S, Kwon Y, Le Thuc O, Hoffmann A, Gil-Lozano M, Karbiener M, Higareda-Almaraz JC, Khani S, Tews D, Fischer-Posovszky P, Sun W, Dong H, Ghosh A, Wolfrum C, Wabitsch M, Virtanen KA, Blüher M, Nielsen S, Zeigerer A, García-Cáceres C, Scheideler M, Herzig S, Bartelt A. Giroud M, et al. Among authors: garcia caceres c. EMBO Rep. 2023 Oct 9;24(10):e57600. doi: 10.15252/embr.202357600. Epub 2023 Sep 6. EMBO Rep. 2023. PMID: 37671834 Free PMC article.
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.
Akindehin S, Liskiewicz A, Liskiewicz D, Bernecker M, Garcia-Caceres C, Drucker DJ, Finan B, Grandl G, Gutgesell R, Hofmann SM, Khalil A, Liu X, Cota P, Bakhti M, Czarnecki O, Bastidas-Ponce A, Lickert H, Kang L, Maity G, Novikoff A, Parlee S, Pathak E, Schriever SC, Sterr M, Ussar S, Zhang Q, DiMarchi R, Tschöp MH, Pfluger PT, Douros JD, Müller TD. Akindehin S, et al. Among authors: garcia caceres c. Mol Metab. 2024 May;83:101915. doi: 10.1016/j.molmet.2024.101915. Epub 2024 Mar 14. Mol Metab. 2024. PMID: 38492844 Free PMC article.
Astrocytic GABA in LHA is an obesity 'thermostat'.
González-García I, García-Cáceres C. González-García I, et al. Among authors: garcia caceres c. Nat Metab. 2023 Sep;5(9):1454-1455. doi: 10.1038/s42255-023-00849-0. Nat Metab. 2023. PMID: 37653042 No abstract available.
Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.
González-García I, García-Clavé E, Cebrian-Serrano A, Le Thuc O, Contreras RE, Xu Y, Gruber T, Schriever SC, Legutko B, Lintelmann J, Adamski J, Wurst W, Müller TD, Woods SC, Pfluger PT, Tschöp MH, Fisette A, García-Cáceres C. González-García I, et al. Among authors: garcia caceres c. Cell Metab. 2023 Mar 7;35(3):438-455.e7. doi: 10.1016/j.cmet.2023.02.004. Cell Metab. 2023. PMID: 36889283 Free PMC article.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
Maity-Kumar G, Ständer L, DeAngelis M, Lee S, Molenaar A, Becker L, Garrett L, Amerie OV, Hoelter SM, Wurst W, Fuchs H, Feuchtinger A, Gailus-Durner V, Garcia-Caceres C, Othman AE, Brockmann C, Schöffling VI, Beiser K, Krude H, Mroz PA, Hofmann S, Tuckermann J, DiMarchi RD, Hrabe de Angelis M, Tschöp MH, Pfluger PT, Müller TD. Maity-Kumar G, et al. Among authors: garcia caceres c. Mol Metab. 2022 Dec;66:101616. doi: 10.1016/j.molmet.2022.101616. Epub 2022 Oct 18. Mol Metab. 2022. PMID: 36270613 Free PMC article.
72 results