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Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target.
Roychowdhury T, Klarin D, Levin MG, Spin JM, Rhee YH, Deng A, Headley CA, Tsao NL, Gellatly C, Zuber V, Shen F, Hornsby WE, Laursen IH, Verma SS, Locke AE, Einarsson G, Thorleifsson G, Graham SE, Dikilitas O, Pattee JW, Judy RL, Pauls-Verges F, Nielsen JB, Wolford BN, Brumpton BM, Dilmé J, Peypoch O, Juscafresa LC, Edwards TL, Li D, Banasik K, Brunak S, Jacobsen RL, Garcia-Barrio MT, Zhang J, Rasmussen LM, Lee R, Handa A, Wanhainen A, Mani K, Lindholt JS, Obel LM, Strauss E, Oszkinis G, Nelson CP, Saxby KL, van Herwaarden JA, van der Laan SW, van Setten J, Camacho M, Davis FM, Wasikowski R, Tsoi LC, Gudjonsson JE, Eliason JL, Coleman DM, Henke PK, Ganesh SK, Chen YE, Guan W, Pankow JS, Pankratz N, Pedersen OB, Erikstrup C, Tang W, Hveem K, Gudbjartsson D, Gretarsdottir S, Thorsteinsdottir U, Holm H, Stefansson K, Ferreira MA, Baras A, Kullo IJ, Ritchie MD, Christensen AH, Iversen KK, Eldrup N, Sillesen H, Ostrowski SR, Bundgaard H, Ullum H, Burgess S, Gill D, Gallagher K, Sabater-Lleal M; DiscovEHR; Regeneron Genetics Center; UK Aneurysm Growth Study; DBDS Genomic Consortium; VA Million Veteran Program; Surakka I, Jones GT, Bown MJ, Tsao PS, Willer CJ, Damrauer SM. Roychowdhury T, et al. Among authors: garcia barrio mt. Nat Genet. 2023 Nov;55(11):1831-1842. doi: 10.1038/s41588-023-01510-y. Epub 2023 Oct 16. Nat Genet. 2023. PMID: 37845353 Free PMC article.
Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.
Roychowdhury T, Lu H, Hornsby WE, Crone B, Wang GT, Guo DC, Sendamarai AK, Devineni P, Lin M, Zhou W, Graham SE, Wolford BN, Surakka I, Wang Z, Chang L, Zhang J, Mathis M, Brummett CM, Melendez TL, Shea MJ, Kim KM, Deeb GM, Patel HJ, Eliason J, Eagle KA, Yang B, Ganesh SK, Brumpton B, Åsvold BO, Skogholt AH, Hveem K; VA Million Veteran Program; Pyarajan S, Klarin D, Tsao PS, Damrauer SM, Leal SM, Milewicz DM, Chen YE, Garcia-Barrio MT, Willer CJ. Roychowdhury T, et al. Among authors: garcia barrio mt. Am J Hum Genet. 2021 Sep 2;108(9):1578-1589. doi: 10.1016/j.ajhg.2021.06.016. Epub 2021 Jul 14. Am J Hum Genet. 2021. PMID: 34265237 Free PMC article.
Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2.
Fan Y, Wolford BN, Lu H, Liang W, Sun J, Zhou W, Rom O, Mahajan A, Surakka I, Graham SE, Liu Z, Kim H, Ramdas S, Fritsche LG, Nielsen JB, Gabrielsen ME, Hveem K, Yang D, Song J, Garcia-Barrio MT, Zhang J, Liu W, Zhang K, Willer CJ, Chen YE. Fan Y, et al. Among authors: garcia barrio mt. iScience. 2021 Oct 2;24(11):103196. doi: 10.1016/j.isci.2021.103196. eCollection 2021 Nov 19. iScience. 2021. PMID: 34746691 Free PMC article.
Revisiting Vascular Remodeling in the Single-Cell Transcriptome Era.
Zhang J, Chang L, Garcia-Barrio MT, Chen YE. Zhang J, et al. Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):1896-1898. doi: 10.1161/ATVBAHA.119.313174. Epub 2019 Sep 25. Arterioscler Thromb Vasc Biol. 2019. PMID: 31553668 Free PMC article. No abstract available.
Brown Adipose Tissue, Not Just a Heater.
Chang L, Garcia-Barrio MT, Chen YE. Chang L, et al. Arterioscler Thromb Vasc Biol. 2017 Mar;37(3):389-391. doi: 10.1161/ATVBAHA.116.308909. Arterioscler Thromb Vasc Biol. 2017. PMID: 28228444 Free PMC article. No abstract available.
Genome engineering technologies in rabbits.
Song J, Zhang J, Xu J, Garcia-Barrio M, Chen YE, Yang D. Song J, et al. J Biomed Res. 2020 Jun 12;35(2):135-147. doi: 10.7555/JBR.34.20190133. J Biomed Res. 2020. PMID: 32934190 Free PMC article.
60 results