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Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors.
Kazi A, Ranjan A, Kumar M V V, Agianian B, Garcia Chavez M, Vudatha V, Wang R, Vangipurapu R, Chen L, Kennedy P, Subramanian K, Quirke JCK, Beato F, Underwood PW, Fleming JB, Trevino J, Hergenrother PJ, Gavathiotis E, Sebti SM. Kazi A, et al. Among authors: garcia chavez m. Cancer Res Commun. 2023 Dec 28;3(12):2623-2639. doi: 10.1158/2767-9764.CRC-23-0222. Cancer Res Commun. 2023. PMID: 38051103 Free PMC article.
Dhilirolides E-N, meroterpenoids produced in culture by the fungus Penicillium purpurogenum collected in Sri Lanka: structure elucidation, stable isotope feeding studies, and insecticidal activity.
Centko RM, Williams DE, Patrick BO, Akhtar Y, Garcia Chavez MA, Wang YA, Isman MB, de Silva ED, Andersen RJ. Centko RM, et al. Among authors: garcia chavez ma. J Org Chem. 2014 Apr 18;79(8):3327-35. doi: 10.1021/jo4024039. Epub 2014 Mar 31. J Org Chem. 2014. PMID: 24684453
Sesterterpenoids isolated from a northeastern Pacific Phorbas sp.
Daoust J, Chen M, Wang M, Williams DE, Garcia Chavez MA, Wang YA, Merchant CE, Fontana A, Kieffer TJ, Andersen RJ. Daoust J, et al. Among authors: garcia chavez ma. J Org Chem. 2013 Sep 6;78(17):8267-73. doi: 10.1021/jo4014589. Epub 2013 Aug 20. J Org Chem. 2013. PMID: 23941043