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Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library.
Alcón-Calderón M, de Lucio H, García-Soriano JC, Revuelto A, de Castro S, López-Gutiérrez C, San-Félix A, Quesada E, Gago F, Camarasa MJ, Jiménez-Ruiz A, Velázquez S. Alcón-Calderón M, et al. Among authors: garcia soriano jc. Eur J Med Chem. 2022 Dec 5;243:114675. doi: 10.1016/j.ejmech.2022.114675. Epub 2022 Aug 18. Eur J Med Chem. 2022. PMID: 36075146 Free article.
New Phosphoramidates Containing Selenium as Leishmanicidal Agents.
Etxebeste-Mitxeltorena M, Plano D, Espuelas S, Moreno E, Aydillo C, Jiménez-Ruiz A, García Soriano JC, Sanmartín C. Etxebeste-Mitxeltorena M, et al. Among authors: garcia soriano jc. Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0059021. doi: 10.1128/AAC.00590-21. Epub 2021 Aug 2. Antimicrob Agents Chemother. 2021. PMID: 34339279 Free PMC article.
Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity.
de Lucio H, Revuelto A, Carriles AA, de Castro S, García-González S, García-Soriano JC, Alcón-Calderón M, Sánchez-Murcia PA, Hermoso JA, Gago F, Camarasa MJ, Jiménez-Ruiz A, Velázquez S. de Lucio H, et al. Among authors: garcia soriano jc. Eur J Med Chem. 2022 Dec 15;244:114878. doi: 10.1016/j.ejmech.2022.114878. Epub 2022 Oct 29. Eur J Med Chem. 2022. PMID: 36332553 Free article.