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A Traditional Chinese Medicine Plant Extract Prevents Alcohol-Induced Osteopenia.
Qian D, Zhou H, Fan P, Yu T, Patel A, O'Brien M, Wang Z, Lu S, Tong G, Shan Y, Wang L, Gao Y, Xiong Y, Zhang L, Wang X, Liu Y, Zhou S. Qian D, et al. Among authors: gao y. Front Pharmacol. 2021 Dec 15;12:754088. doi: 10.3389/fphar.2021.754088. eCollection 2021. Front Pharmacol. 2021. PMID: 35002697 Free PMC article.
Megalin mediates 25-hydroxyvitamin D3 actions in human mesenchymal stem cells.
Gao Y, Zhou S, Luu S, Glowacki J. Gao Y, et al. FASEB J. 2019 Jun;33(6):7684-7693. doi: 10.1096/fj.201802578R. Epub 2019 Mar 20. FASEB J. 2019. PMID: 30893561
These studies show that megalin is expressed in hMSCs and is required for the biosynthesis of 1alpha,25(OH)(2)D(3) and for the 25(OH)D(3)/DBP complex to stimulate vitamin D receptor targets and osteoblastogenesis.-Gao, Y., Zhou, S., Luu, S., Glowacki, J. Megalin med …
These studies show that megalin is expressed in hMSCs and is required for the biosynthesis of 1alpha,25(OH)(2)D(3) and for the 25(OH)D(3)/DB …
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