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Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy.
Liu YC, Kwon J, Fabiani E, Xiao Z, Liu YV, Follo MY, Liu J, Huang H, Gao C, Liu J, Falconi G, Valentini L, Gurnari C, Finelli C, Cocco L, Liu JH, Jones AI, Yang J, Yang H, Thoms JAI, Unnikrishnan A, Pimanda JE, Pan R, Bassal MA, Voso MT, Tenen DG, Chai L. Liu YC, et al. Among authors: gao c. N Engl J Med. 2022 May 26;386(21):1998-2010. doi: 10.1056/NEJMoa2119771. N Engl J Med. 2022. PMID: 35613022 Free PMC article.
The role of stem cell factor SALL4 in leukemogenesis.
Gao C, Kong NR, Chai L. Gao C, et al. Crit Rev Oncog. 2011;16(1-2):117-27. doi: 10.1615/critrevoncog.v16.i1-2.110. Crit Rev Oncog. 2011. PMID: 22150312 Free PMC article. Review.
SALL4 is a key transcription regulator in normal human hematopoiesis.
Gao C, Kong NR, Li A, Tatetu H, Ueno S, Yang Y, He J, Yang J, Ma Y, Kao GS, Tenen DG, Chai L. Gao C, et al. Transfusion. 2013 May;53(5):1037-49. doi: 10.1111/j.1537-2995.2012.03888.x. Epub 2012 Aug 31. Transfusion. 2013. PMID: 22934838 Free PMC article.
Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.
Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG. Yong KJ, et al. Among authors: gao c. N Engl J Med. 2013 Jun 13;368(24):2266-76. doi: 10.1056/NEJMoa1300297. N Engl J Med. 2013. PMID: 23758232 Free PMC article.
Targeting an Inducible SALL4-Mediated Cancer Vulnerability with Sequential Therapy.
Yang J, Gao C, Liu M, Liu YC, Kwon J, Qi J, Tian X, Stein A, Liu YV, Kong NR, Wu Y, Yin S, Xi J, Chen Z, Kumari K, Wong H, Luo H, Silberstein LE, Thoms JAI, Unnikrishnan A, Pimanda JE, Tenen DG, Chai L. Yang J, et al. Among authors: gao c. Cancer Res. 2021 Dec 1;81(23):6018-6028. doi: 10.1158/0008-5472.CAN-21-0030. Epub 2021 Sep 30. Cancer Res. 2021. PMID: 34593523 Free PMC article.
Pseudogene-mediated DNA demethylation leads to oncogene activation.
Kwon J, Liu YV, Gao C, Bassal MA, Jones AI, Yang J, Chen Z, Li Y, Yang H, Chen L, Di Ruscio A, Tay Y, Chai L, Tenen DG. Kwon J, et al. Among authors: gao c. Sci Adv. 2021 Oct;7(40):eabg1695. doi: 10.1126/sciadv.abg1695. Epub 2021 Oct 1. Sci Adv. 2021. PMID: 34597139 Free PMC article.
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