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Nirmatrelvir-resistant SARS-CoV-2 variants with high fitness in an infectious cell culture system.
Zhou Y, Gammeltoft KA, Ryberg LA, Pham LV, Tjørnelund HD, Binderup A, Duarte Hernandez CR, Fernandez-Antunez C, Offersgaard A, Fahnøe U, Peters GHJ, Ramirez S, Bukh J, Gottwein JM. Zhou Y, et al. Among authors: gammeltoft ka. Sci Adv. 2022 Dec 21;8(51):eadd7197. doi: 10.1126/sciadv.add7197. Epub 2022 Dec 21. Sci Adv. 2022. PMID: 36542720 Free PMC article.
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 In Vitro.
Gammeltoft KA, Zhou Y, Duarte Hernandez CR, Galli A, Offersgaard A, Costa R, Pham LV, Fahnøe U, Feng S, Scheel TKH, Ramirez S, Bukh J, Gottwein JM. Gammeltoft KA, et al. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0268020. doi: 10.1128/AAC.02680-20. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34097489 Free PMC article.
In vitro efficacy of artemisinin-based treatments against SARS-CoV-2.
Zhou Y, Gilmore K, Ramirez S, Settels E, Gammeltoft KA, Pham LV, Fahnøe U, Feng S, Offersgaard A, Trimpert J, Bukh J, Osterrieder K, Gottwein JM, Seeberger PH. Zhou Y, et al. Among authors: gammeltoft ka. Sci Rep. 2021 Jul 16;11(1):14571. doi: 10.1038/s41598-021-93361-y. Sci Rep. 2021. PMID: 34272426 Free PMC article.
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals.
Offersgaard A, Duarte Hernandez CR, Feng S, Marichal-Gallardo P, Holmbeck K, Pihl AF, Fernandez-Antunez C, Alzua GP, Hartmann KT, Pham LV, Zhou Y, Gammeltoft KA, Fahnøe U, Schneider UV, Pedersen GK, Jensen HE, Christensen JP, Ramirez S, Bukh J, Gottwein JM. Offersgaard A, et al. Among authors: gammeltoft ka. iScience. 2023 Feb 17;26(2):105949. doi: 10.1016/j.isci.2023.105949. Epub 2023 Jan 10. iScience. 2023. PMID: 36644321 Free PMC article.
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Tran DHN, Agrawal A, Ghita L, Ojha A, East MP, Gammeltoft KA, Sahoo MK, Johnson GL, Das S, Jochmans D, Cohen CA, Gottwein J, Dye J, Neff N, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, Jonghe S, Asquith CRM, Einav S. Karim M, et al. Among authors: gammeltoft ka. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589676. doi: 10.1101/2024.04.15.589676. bioRxiv. 2024. PMID: 38659941 Free PMC article. Preprint.