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Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Linder SJ, Bernasocchi T, Martínez-Pastor B, Sullivan KD, Galbraith MD, Lewis CA, Ferrer CM, Boon R, Silveira GG, Cho HM, Vidoudez C, Shroff S, Oliveira-Costa JP, Ross KN, Massri R, Matoba Y, Kim E, Rueda BR, Stott SL, Gottlieb E, Espinosa JM, Mostoslavsky R. Linder SJ, et al. Among authors: galbraith md. Nat Metab. 2023 Dec;5(12):2131-2147. doi: 10.1038/s42255-023-00919-3. Epub 2023 Nov 13. Nat Metab. 2023. PMID: 37957387
Mechanisms of transcriptional regulation by p53.
Sullivan KD, Galbraith MD, Andrysik Z, Espinosa JM. Sullivan KD, et al. Among authors: galbraith md. Cell Death Differ. 2018 Jan;25(1):133-143. doi: 10.1038/cdd.2017.174. Epub 2017 Nov 10. Cell Death Differ. 2018. PMID: 29125602 Free PMC article. Review.
CDK8: a positive regulator of transcription.
Galbraith MD, Donner AJ, Espinosa JM. Galbraith MD, et al. Transcription. 2010 Jul-Aug;1(1):4-12. doi: 10.4161/trns.1.1.12373. Transcription. 2010. PMID: 21327159 Free PMC article. Review.
Trisomy 21 consistently activates the interferon response.
Sullivan KD, Lewis HC, Hill AA, Pandey A, Jackson LP, Cabral JM, Smith KP, Liggett LA, Gomez EB, Galbraith MD, DeGregori J, Espinosa JM. Sullivan KD, et al. Among authors: galbraith md. Elife. 2016 Jul 29;5:e16220. doi: 10.7554/eLife.16220. Elife. 2016. PMID: 27472900 Free PMC article.
46 results