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Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase (MtDTBS): Toward Next-Generation Antituberculosis Agents.
ACS Chem Biol. 2021 Nov 19;16(11):2339-2347. doi: 10.1021/acschembio.1c00491. Epub 2021 Sep 17.
ACS Chem Biol. 2021.
PMID: 34533923
Fortuitous In Vitro Compound Degradation Produces a Tractable Hit against Mycobacterium tuberculosis Dethiobiotin Synthetase: A Cautionary Tale of What Goes In Does Not Always Come Out.
Salaemae W, Thompson AP, Gaiser BI, Lee KJ, Huxley MT, Sumby CJ, Polyak SW, Abell AD, Bruning JB, Wegener KL.
Salaemae W, et al. Among authors: gaiser bi.
ACS Chem Biol. 2023 Sep 15;18(9):1985-1992. doi: 10.1021/acschembio.3c00215. Epub 2023 Aug 31.
ACS Chem Biol. 2023.
PMID: 37651626
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Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands.
Gaiser BI, Danielsen M, Marcher-Rørsted E, Røpke Jørgensen K, Wróbel TM, Frykman M, Johansson H, Bräuner-Osborne H, Gloriam DE, Mathiesen JM, Sejer Pedersen D.
Gaiser BI, et al.
J Med Chem. 2019 Sep 12;62(17):7806-7839. doi: 10.1021/acs.jmedchem.9b00595. Epub 2019 Aug 15.
J Med Chem. 2019.
PMID: 31298548
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Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry.
Fronik P, Gaiser BI, Sejer Pedersen D.
Fronik P, et al. Among authors: gaiser bi.
J Med Chem. 2017 May 25;60(10):4126-4134. doi: 10.1021/acs.jmedchem.6b01601. Epub 2017 Feb 15.
J Med Chem. 2017.
PMID: 28140580
Review.
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