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UBTD1 is a mechano-regulator controlling cancer aggressiveness.
Torrino S, Roustan FR, Kaminski L, Bertero T, Pisano S, Ambrosetti D, Dufies M, Uhler JP, Lemichez E, Mettouchi A, Gesson M, Laurent K, Gaggioli C, Michiels JF, Lamaze C, Bost F, Clavel S. Torrino S, et al. Among authors: gaggioli c. EMBO Rep. 2019 Apr;20(4):e46570. doi: 10.15252/embr.201846570. Epub 2019 Feb 25. EMBO Rep. 2019. PMID: 30804013 Free PMC article.
LIF mediates proinvasive activation of stromal fibroblasts in cancer.
Albrengues J, Bourget I, Pons C, Butet V, Hofman P, Tartare-Deckert S, Feral CC, Meneguzzi G, Gaggioli C. Albrengues J, et al. Among authors: gaggioli c. Cell Rep. 2014 Jun 12;7(5):1664-1678. doi: 10.1016/j.celrep.2014.04.036. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857661 Free article.
p38MAPK builds a hyaluronan cancer niche to drive lung tumorigenesis.
Brichkina A, Bertero T, Loh HM, Nguyen NT, Emelyanov A, Rigade S, Ilie M, Hofman P, Gaggioli C, Bulavin DV. Brichkina A, et al. Among authors: gaggioli c. Genes Dev. 2016 Dec 1;30(23):2623-2636. doi: 10.1101/gad.290346.116. Genes Dev. 2016. PMID: 28007785 Free PMC article.
Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells.
Grasset EM, Bertero T, Bozec A, Friard J, Bourget I, Pisano S, Lecacheur M, Maiel M, Bailleux C, Emelyanov A, Ilie M, Hofman P, Meneguzzi G, Duranton C, Bulavin DV, Gaggioli C. Grasset EM, et al. Among authors: gaggioli c. Cancer Res. 2018 Sep 15;78(18):5229-5242. doi: 10.1158/0008-5472.CAN-18-0601. Epub 2018 Jul 19. Cancer Res. 2018. PMID: 30026329
Mechanical forces rewire metabolism in the tumor niche.
Bertero T, Gaggioli C. Bertero T, et al. Among authors: gaggioli c. Mol Cell Oncol. 2019 Mar 25;6(3):1592945. doi: 10.1080/23723556.2019.1592945. eCollection 2019. Mol Cell Oncol. 2019. PMID: 31131310 Free PMC article.
A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma.
Girard CA, Lecacheur M, Ben Jouira R, Berestjuk I, Diazzi S, Prod'homme V, Mallavialle A, Larbret F, Gesson M, Schaub S, Pisano S, Audebert S, Mari B, Gaggioli C, Leucci E, Marine JC, Deckert M, Tartare-Deckert S. Girard CA, et al. Among authors: gaggioli c. Cancer Res. 2020 May 15;80(10):1927-1941. doi: 10.1158/0008-5472.CAN-19-2914. Epub 2020 Mar 16. Cancer Res. 2020. PMID: 32179513 Free article.
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma.
Berestjuk I, Lecacheur M, Carminati A, Diazzi S, Rovera C, Prod'homme V, Ohanna M, Popovic A, Mallavialle A, Larbret F, Pisano S, Audebert S, Passeron T, Gaggioli C, Girard CA, Deckert M, Tartare-Deckert S. Berestjuk I, et al. Among authors: gaggioli c. EMBO Mol Med. 2022 Feb 7;14(2):e11814. doi: 10.15252/emmm.201911814. Epub 2021 Dec 27. EMBO Mol Med. 2022. PMID: 34957688 Free PMC article.
64 results