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The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling.
Chen B, Dragomir MP, Fabris L, Bayraktar R, Knutsen E, Liu X, Tang C, Li Y, Shimura T, Ivkovic TC, De Los Santos MC, Anfossi S, Shimizu M, Shah MY, Ling H, Shen P, Multani AS, Pardini B, Burks JK, Katayama H, Reineke LC, Huo L, Syed M, Song S, Ferracin M, Oki E, Fromm B, Ivan C, Bhuvaneshwar K, Gusev Y, Mimori K, Menter D, Sen S, Matsuyama T, Uetake H, Vasilescu C, Kopetz S, Parker-Thornburg J, Taguchi A, Hanash SM, Girnita L, Slaby O, Goel A, Varani G, Gagea M, Li C, Ajani JA, Calin GA. Chen B, et al. Among authors: gagea m. Gastroenterology. 2020 Dec;159(6):2146-2162.e33. doi: 10.1053/j.gastro.2020.08.018. Epub 2020 Aug 15. Gastroenterology. 2020. PMID: 32805281 Free PMC article.
Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer.
Treekitkarnmongkol W, Katayama H, Kai K, Sasai K, Jones JC, Wang J, Shen L, Sahin AA, Gagea M, Ueno NT, Creighton CJ, Sen S. Treekitkarnmongkol W, et al. Among authors: gagea m. Carcinogenesis. 2016 Dec;37(12):1180-1189. doi: 10.1093/carcin/bgw097. Epub 2016 Sep 13. Carcinogenesis. 2016. PMID: 27624071 Free PMC article.
Metastasis regulation by PPARD expression in cancer cells.
Zuo X, Xu W, Xu M, Tian R, Moussalli MJ, Mao F, Zheng X, Wang J, Morris JS, Gagea M, Eng C, Kopetz S, Maru DM, Rashid A, Broaddus R, Wei D, Hung MC, Sood AK, Shureiqi I. Zuo X, et al. Among authors: gagea m. JCI Insight. 2017 Jan 12;2(1):e91419. doi: 10.1172/jci.insight.91419. JCI Insight. 2017. PMID: 28097239 Free PMC article.
Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.
Shah MY, Ferracin M, Pileczki V, Chen B, Redis R, Fabris L, Zhang X, Ivan C, Shimizu M, Rodriguez-Aguayo C, Dragomir M, Van Roosbroeck K, Almeida MI, Ciccone M, Nedelcu D, Cortez MA, Manshouri T, Calin S, Muftuoglu M, Banerjee PP, Badiwi MH, Parker-Thornburg J, Multani A, Welsh JW, Estecio MR, Ling H, Tomuleasa C, Dima D, Yang H, Alvarez H, You MJ, Radovich M, Shpall E, Fabbri M, Rezvani K, Girnita L, Berindan-Neagoe I, Maitra A, Verstovsek S, Fodde R, Bueso-Ramos C, Gagea M, Manero GG, Calin GA. Shah MY, et al. Among authors: gagea m. Genome Res. 2018 Apr;28(4):432-447. doi: 10.1101/gr.225128.117. Epub 2018 Mar 22. Genome Res. 2018. PMID: 29567676 Free PMC article.
PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice.
Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, Gagea M, Sebastian MM, Zheng X, Tan D, Broaddus R, Wang J, Ajami NJ, Swennes AG, Watowich SS, Shureiqi I. Zuo X, et al. Among authors: gagea m. Gastroenterology. 2019 Jul;157(1):163-178. doi: 10.1053/j.gastro.2019.03.018. Epub 2019 Mar 15. Gastroenterology. 2019. PMID: 30885780 Free PMC article.
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.
Shah VV, Duncan AD, Jiang S, Stratton SA, Allton KL, Yam C, Jain A, Krause PM, Lu Y, Cai S, Tu Y, Zhou X, Zhang X, Jiang Y, Carroll CL, Kang Z, Liu B, Shen J, Gagea M, Manu SM, Huo L, Gilcrease M, Powell RT, Guo L, Stephan C, Davies PJ, Parker-Thornburg J, Lozano G, Behringer RR, Piwnica-Worms H, Chang JT, Moulder SL, Barton MC. Shah VV, et al. Among authors: gagea m. Nat Commun. 2021 Sep 10;12(1):5389. doi: 10.1038/s41467-021-25650-z. Nat Commun. 2021. PMID: 34508101 Free PMC article.
Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment.
Liu S, Xie SM, Liu W, Gagea M, Hanker AB, Nguyen N, Raghavendra AS, Yang-Kolodji G, Chu F, Neelapu SS, Hanash S, Zimmermann J, Arteaga CL, Tripathy D. Liu S, et al. Among authors: gagea m. Res Sq [Preprint]. 2023 Feb 14:rs.3.rs-2388864. doi: 10.21203/rs.3.rs-2388864/v1. Res Sq. 2023. PMID: 36824840 Free PMC article. Updated. Preprint.
Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment.
Liu S, Xie SM, Liu W, Gagea M, Hanker AB, Nguyen N, Singareeka Raghavendra A, Yang-Kolodji G, Chu F, Neelapu SS, Marchese A, Hanash S, Zimmermann J, Arteaga CL, Tripathy D. Liu S, et al. Among authors: gagea m. Breast Cancer Res. 2023 Jun 6;25(1):62. doi: 10.1186/s13058-023-01665-w. Breast Cancer Res. 2023. PMID: 37280713 Free PMC article.
95 results