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IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.
Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL. Conti HR, et al. Among authors: gaffen sl. Cell Host Microbe. 2016 Nov 9;20(5):606-617. doi: 10.1016/j.chom.2016.10.001. Epub 2016 Oct 27. Cell Host Microbe. 2016. PMID: 27923704 Free PMC article.
Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.
Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, Gaffen SL. Verma AH, et al. Among authors: gaffen sl. Sci Immunol. 2017 Nov 3;2(17):eaam8834. doi: 10.1126/sciimmunol.aam8834. Sci Immunol. 2017. PMID: 29101209 Free PMC article.
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence.
Richardson JP, Mogavero S, Moyes DL, Blagojevic M, Krüger T, Verma AH, Coleman BM, De La Cruz Diaz J, Schulz D, Ponde NO, Carrano G, Kniemeyer O, Wilson D, Bader O, Enoiu SI, Ho J, Kichik N, Gaffen SL, Hube B, Naglik JR. Richardson JP, et al. Among authors: gaffen sl. mBio. 2018 Jan 23;9(1):e02178-17. doi: 10.1128/mBio.02178-17. mBio. 2018. PMID: 29362237 Free PMC article.
IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms.
Verma AH, Zafar H, Ponde NO, Hepworth OW, Sihra D, Aggor FEY, Ainscough JS, Ho J, Richardson JP, Coleman BM, Hube B, Stacey M, McGeachy MJ, Naglik JR, Gaffen SL, Moyes DL. Verma AH, et al. Among authors: gaffen sl. J Immunol. 2018 Jul 15;201(2):627-634. doi: 10.4049/jimmunol.1800515. Epub 2018 Jun 11. J Immunol. 2018. PMID: 29891557 Free PMC article.
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor.
Ho J, Yang X, Nikou SA, Kichik N, Donkin A, Ponde NO, Richardson JP, Gratacap RL, Archambault LS, Zwirner CP, Murciano C, Henley-Smith R, Thavaraj S, Tynan CJ, Gaffen SL, Hube B, Wheeler RT, Moyes DL, Naglik JR. Ho J, et al. Among authors: gaffen sl. Nat Commun. 2019 May 24;10(1):2297. doi: 10.1038/s41467-019-09915-2. Nat Commun. 2019. PMID: 31127085 Free PMC article.
Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis.
Aggor FEY, Break TJ, Trevejo-Nuñez G, Whibley N, Coleman BM, Bailey RD, Kaplan DH, Naglik JR, Shan W, Shetty AC, McCracken C, Durum SK, Biswas PS, Bruno VM, Kolls JK, Lionakis MS, Gaffen SL. Aggor FEY, et al. Among authors: gaffen sl. Sci Immunol. 2020 Jun 5;5(48):eaba0570. doi: 10.1126/sciimmunol.aba0570. Sci Immunol. 2020. PMID: 32503875 Free PMC article.
149 results