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Systems-based digital twins to help characterize clinical dose-response and propose predictive biomarkers in a Phase I study of bispecific antibody, mosunetuzumab, in NHL.
Susilo ME, Li CC, Gadkar K, Hernandez G, Huw LY, Jin JY, Yin S, Wei MC, Ramanujan S, Hosseini I. Susilo ME, et al. Among authors: gadkar k. Clin Transl Sci. 2023 Jul;16(7):1134-1148. doi: 10.1111/cts.13501. Epub 2023 Mar 23. Clin Transl Sci. 2023. PMID: 36908269 Free PMC article. Clinical Trial.
Quantitative systems pharmacology model-based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3-kinase inhibitors.
Gadkar K, Friedrich C, Hurez V, Ruiz ML, Dickmann L, Kumar Jolly M, Schutt L, Jin J, Ware JA, Ramanujan S. Gadkar K, et al. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):616-627. doi: 10.1002/psp4.12749. Epub 2021 Dec 13. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 34850607 Free PMC article.
38 results