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Development of a Microfluidic Culture Paradigm for Ex Vivo Maintenance of Human Glioblastoma Tissue: A New Glioblastoma Model?
Olubajo F, Achawal S, Greenman J. Olubajo F, et al. Transl Oncol. 2020 Jan;13(1):1-10. doi: 10.1016/j.tranon.2019.09.002. Epub 2019 Nov 11. Transl Oncol. 2020. PMID: 31726354 Free PMC article.
CONCLUSIONS: This work has demonstrated for the first time that human glioblastoma tissue can be successfully maintained within a microfluidic device and has the potential to be developed as a new platform for studying the biology of brain tumours, with the long-term aim of re …
CONCLUSIONS: This work has demonstrated for the first time that human glioblastoma tissue can be successfully maintained within a microfluid …
Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.
Pridgeon CS, Schlott C, Wong MW, Heringa MB, Heckel T, Leedale J, Launay L, Gryshkova V, Przyborski S, Bearon RN, Wilkinson EL, Ansari T, Greenman J, Hendriks DFG, Gibbs S, Sidaway J, Sison-Young RL, Walker P, Cross MJ, Park BK, Goldring CEP. Pridgeon CS, et al. Arch Toxicol. 2018 Feb;92(2):557-569. doi: 10.1007/s00204-018-2152-9. Epub 2018 Jan 23. Arch Toxicol. 2018. PMID: 29362863 Free PMC article. Review.
Accepted methods for gathering the information required by law for approval of substances are often animal methods. To reduce, refine, and replace animal testing, innovative organotypic in vitro models have emerged. ...
Accepted methods for gathering the information required by law for approval of substances are often animal methods. To reduce, refine, and …
Looking to the future of organs-on-chip.
Greenman J. Greenman J. Future Sci OA. 2017 May 26;3(2):FSO205. doi: 10.4155/fsoa-2017-0040. eCollection 2017 Jun. Future Sci OA. 2017. PMID: 28670479 Free PMC article. No abstract available.
13 results