G0900775/1/NC3RS_/National Centre for the Replacement, Refinement and Reduction of Animals in Research/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2011	6
2012	5
2013	2
2014	2
2015	4
2016	1
2017	1
2018	1
2024	0

1

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders.

Augustin K, Khabbush A, Williams S, Eaton S, Orford M, Cross JH, Heales SJR, Walker MC, Williams RSB. Augustin K, et al. Lancet Neurol. 2018 Jan;17(1):84-93. doi: 10.1016/S1474-4422(17)30408-8. Epub 2017 Dec 16. Lancet Neurol. 2018. PMID: 29263011 Review.

2

Seizure control by decanoic acid through direct AMPA receptor inhibition.

Chang P, Augustin K, Boddum K, Williams S, Sun M, Terschak JA, Hardege JD, Chen PE, Walker MC, Williams RS. Chang P, et al. Brain. 2016 Feb;139(Pt 2):431-43. doi: 10.1093/brain/awv325. Epub 2015 Nov 25. Brain. 2016. PMID: 26608744 Free PMC article.

3

New experimental therapies for status epilepticus in preclinical development.

Walker MC, Williams RS. Walker MC, et al. Epilepsy Behav. 2015 Aug;49:290-3. doi: 10.1016/j.yebeh.2015.06.009. Epub 2015 Jul 17. Epilepsy Behav. 2015. PMID: 26189787 Review.

4

Epilepsy research methods update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms.

Cunliffe VT, Baines RA, Giachello CN, Lin WH, Morgan A, Reuber M, Russell C, Walker MC, Williams RS. Cunliffe VT, et al. Seizure. 2015 Jan;24:44-51. doi: 10.1016/j.seizure.2014.09.018. Epub 2014 Oct 13. Seizure. 2015. PMID: 25457452 Free article. Review.

5

Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency.

Chang P, Zuckermann AM, Williams S, Close AJ, Cano-Jaimez M, McEvoy JP, Spencer J, Walker MC, Williams RS. Chang P, et al. J Pharmacol Exp Ther. 2015 Jan;352(1):43-52. doi: 10.1124/jpet.114.218768. Epub 2014 Oct 17. J Pharmacol Exp Ther. 2015. PMID: 25326131

6

Zizimin and Dock guanine nucleotide exchange factors in cell function and disease.

Pakes NK, Veltman DM, Williams RS. Pakes NK, et al. Small GTPases. 2013 Jan-Mar;4(1):22-7. doi: 10.4161/sgtp.22087. Epub 2012 Dec 17. Small GTPases. 2013. PMID: 23247359 Free PMC article.

7

Seizure control by ketogenic diet-associated medium chain fatty acids.

Chang P, Terbach N, Plant N, Chen PE, Walker MC, Williams RS. Chang P, et al. Neuropharmacology. 2013 Jun;69:105-14. doi: 10.1016/j.neuropharm.2012.11.004. Epub 2012 Nov 20. Neuropharmacology. 2013. PMID: 23177536 Free PMC article.

8

The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium.

Pakes NK, Veltman DM, Rivero F, Nasir J, Insall R, Williams RS. Pakes NK, et al. J Cell Sci. 2012 May 15;125(Pt 10):2457-65. doi: 10.1242/jcs.100966. Epub 2012 Feb 24. J Cell Sci. 2012. PMID: 22366457 Free article.

Fluorescently labelled ZizA protein associates with the microtubule-organising centre (MTOC), whereas ZizB is enriched in the cortex. Overexpression of ZizB also causes an increase in the number of filopodia and a partial inhibition of cytokinesis. ...

Fluorescently labelled ZizA protein associates with the microtubule-organising centre (MTOC), whereas ZizB is enriched in the cortex. …

9

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.

Elphick LM, Pawolleck N, Guschina IA, Chaieb L, Eikel D, Nau H, Harwood JL, Plant NJ, Williams RS. Elphick LM, et al. Dis Model Mech. 2012 Mar;5(2):231-40. doi: 10.1242/dmm.008391. Epub 2011 Oct 14. Dis Model Mech. 2012. PMID: 22003123 Free PMC article.

10

Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research.

Robery S, Mukanowa J, Percie du Sert N, Andrews PL, Williams RS. Robery S, et al. PLoS One. 2011;6(9):e24439. doi: 10.1371/journal.pone.0024439. Epub 2011 Sep 8. PLoS One. 2011. PMID: 21931717 Free PMC article.

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