Gütschow M - Search Results

1

Studies on the affinity of 6-[(n-(cyclo)aminoalkyl)oxy]-4H-chromen-4-ones for sigma 1/2 receptors.

Deuther-Conrad W, Diez-Iriepa D, Iriepa I, López-Muñoz F, Martínez-Grau MA, Gütschow M, Marco-Contelles J. Deuther-Conrad W, et al. Among authors: gutschow m. RSC Med Chem. 2021 May 20;12(6):1000-1004. doi: 10.1039/d1md00105a. eCollection 2021 Jun 23. RSC Med Chem. 2021. PMID: 34223165 Free PMC article.

2

First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.

Elsinghorst PW, Cieslik JS, Mohr K, Tränkle C, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. J Med Chem. 2007 Nov 15;50(23):5685-95. doi: 10.1021/jm070859s. Epub 2007 Oct 18. J Med Chem. 2007. PMID: 17944454

3

Benzothiazinones: a novel class of adenosine receptor antagonists structurally unrelated to xanthine and adenine derivatives.

Gütschow M, Schlenk M, Gäb J, Paskaleva M, Alnouri MW, Scolari S, Iqbal J, Müller CE. Gütschow M, et al. J Med Chem. 2012 Apr 12;55(7):3331-41. doi: 10.1021/jm300029s. Epub 2012 Mar 27. J Med Chem. 2012. PMID: 22409573

4

Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.

Stössel A, Schlenk M, Hinz S, Küppers P, Heer J, Gütschow M, Müller CE. Stössel A, et al. Among authors: gutschow m. J Med Chem. 2013 Jun 13;56(11):4580-96. doi: 10.1021/jm400336x. Epub 2013 May 30. J Med Chem. 2013. PMID: 23631427

5

Chromenones as Multineurotargeting Inhibitors of Human Enzymes.

Lemke C, Christmann J, Yin J, Alonso JM, Serrano E, Chioua M, Ismaili L, Martínez-Grau MA, Beadle CD, Vetman T, Dato FM, Bartz U, Elsinghorst PW, Pietsch M, Müller CE, Iriepa I, Wille T, Marco-Contelles J, Gütschow M. Lemke C, et al. Among authors: gutschow m. ACS Omega. 2019 Dec 11;4(26):22161-22168. doi: 10.1021/acsomega.9b03409. eCollection 2019 Dec 24. ACS Omega. 2019. PMID: 31891098 Free PMC article.

6

The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents.

Keuler T, Lemke C, Elsinghorst PW, Iriepa I, Chioua M, Martínez-Grau MA, Beadle CD, Vetman T, López-Muñoz F, Wille T, Bartz U, Deuther-Conrad W, Marco-Contelles J, Gütschow M. Keuler T, et al. Among authors: gutschow m. ACS Pharmacol Transl Sci. 2022 Oct 12;5(11):1097-1108. doi: 10.1021/acsptsci.2c00097. eCollection 2022 Nov 11. ACS Pharmacol Transl Sci. 2022. PMID: 36407962 Free PMC article.

7

Inhibition of cathepsin G by 4H-3,1-benzoxazin-4-ones.

Gütschow M, Neumann U. Gütschow M, et al. Bioorg Med Chem. 1997 Oct;5(10):1935-42. doi: 10.1016/s0968-0896(97)00128-4. Bioorg Med Chem. 1997. PMID: 9370038

8

2-(diethylamino)thieno1,3ŏxazin-4-ones as stable inhibitors of human leukocyte elastase.

Gütschow M, Kuerschner L, Neumann U, Pietsch M, Löser R, Koglin N, Eger K. Gütschow M, et al. J Med Chem. 1999 Dec 30;42(26):5437-47. doi: 10.1021/jm991108w. J Med Chem. 1999. PMID: 10639285

9

Synthesis of tricyclic 1,3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition.

Pietsch M, Gütschow M. Pietsch M, et al. Among authors: gutschow m. J Med Chem. 2005 Dec 29;48(26):8270-88. doi: 10.1021/jm0508639. J Med Chem. 2005. PMID: 16366609

10

Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase.

Elsinghorst PW, Tanarro CM, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. J Med Chem. 2006 Dec 14;49(25):7540-4. doi: 10.1021/jm060742o. J Med Chem. 2006. PMID: 17149883

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