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PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective.
Orozco Morales ML, Rinaldi CA, de Jong E, Lansley SM, Gummer JPA, Olasz B, Nambiar S, Hope DE, Casey TH, Lee YCG, Leslie C, Nealon G, Shackleford DM, Powell AK, Grimaldi M, Balaguer P, Zemek RM, Bosco A, Piggott MJ, Vrielink A, Lake RA, Lesterhuis WJ. Orozco Morales ML, et al. Among authors: gummer jpa. iScience. 2021 Dec 4;25(1):103571. doi: 10.1016/j.isci.2021.103571. eCollection 2022 Jan 21. iScience. 2021. PMID: 34984327 Free PMC article.
Probiotics and sepsis: separating the signal from the noise.
Litton E, Currie A, Raby E; ROCIT Investigators. Litton E, et al. Intensive Care Med. 2021 Aug;47(8):924-925. doi: 10.1007/s00134-021-06427-w. Epub 2021 May 20. Intensive Care Med. 2021. PMID: 34014376 No abstract available.
Early and sustained Lactobacillus plantarum probiotic therapy in critical illness: the randomised, placebo-controlled, restoration of gut microflora in critical illness trial (ROCIT).
Litton E, Anstey M, Broadhurst D, Chapman A, Currie A, Ferrier J, Gummer J, Higgins A, Lim J, Manning L, Myers E, Orr K, Palermo AM, Paparini A, Pellicano S, Raby E, Rammohan A, Regli A, Richter B, Salman S, Strunk T, Waterson S, Weight D, Wibrow B, Wood F. Litton E, et al. Among authors: gummer j. Intensive Care Med. 2021 Mar;47(3):307-315. doi: 10.1007/s00134-020-06322-w. Epub 2021 Feb 10. Intensive Care Med. 2021. PMID: 33566129 Free PMC article. Clinical Trial.
Study protocol for the safety and efficacy of probiotic therapy on days alive and out of hospital in adult ICU patients: the multicentre, randomised, placebo-controlled Restoration Of gut microflora in Critical Illness Trial (ROCIT).
Litton E, Anstey M, Broadhurst D, Chapman AR, Currie A, Ferrier J, Gummer J, Higgins A, Lim J, Manning L, Myers E, Orr K, Palermo AM, Paparini A, Pellicano S, Raby E, Rammohan A, Regli A, Richter B, Salman S, Strunk T, Waterson S, Wibrow B, Wood FM. Litton E, et al. Among authors: gummer j. BMJ Open. 2020 Jun 21;10(6):e035930. doi: 10.1136/bmjopen-2019-035930. BMJ Open. 2020. PMID: 32565465 Free PMC article.
43 results