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Page 1
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, Burchert A, Huber M, Friebus-Kardash J, Göthert JR, Hardt C, Probst HC, Schumacher F, Köhrer K, Kleuser B, Babiychuk EB, Sodeik B, Seibel J, Greber UF, Lang PA, Gulbins E, Lang KS. Lang J, et al. Among authors: gothert jr. Nat Commun. 2020 Mar 12;11(1):1338. doi: 10.1038/s41467-020-15072-8. Nat Commun. 2020. PMID: 32165633 Free PMC article.
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.
Khairnar V, Duhan V, Maney SK, Honke N, Shaabani N, Pandyra AA, Seifert M, Pozdeev V, Xu HC, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf AM, Häussinger D, Lang F, Dittmer U, Küppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Göthert JR, Singer BB, Lang PA, Lang KS. Khairnar V, et al. Among authors: gothert jr. Nat Commun. 2015 Feb 18;6:6217. doi: 10.1038/ncomms7217. Nat Commun. 2015. PMID: 25692415 Free PMC article.
CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.
Khairnar V, Duhan V, Patil AM, Zhou F, Bhat H, Thoens C, Sharma P, Adomati T, Friendrich SK, Bezgovsek J, Dreesen JD, Wennemuth G, Westendorf AM, Zelinskyy G, Dittmer U, Hardt C, Timm J, Göthert JR, Lang PA, Singer BB, Lang KS. Khairnar V, et al. Among authors: gothert jr. Nat Commun. 2018 Jul 2;9(1):2561. doi: 10.1038/s41467-018-04832-2. Nat Commun. 2018. PMID: 29967450 Free PMC article.
Pathological manifestations of Farber disease in a new mouse model.
Beckmann N, Kadow S, Schumacher F, Göthert JR, Kesper S, Draeger A, Schulz-Schaeffer WJ, Wang J, Becker JU, Kramer M, Kühn C, Kleuser B, Becker KA, Gulbins E, Carpinteiro A. Beckmann N, et al. Among authors: gothert jr. Biol Chem. 2018 Sep 25;399(10):1183-1202. doi: 10.1515/hsz-2018-0170. Biol Chem. 2018. PMID: 29908121 Free article.
Regulation of Arthritis Severity by the Acid Sphingomyelinase.
Beckmann N, Becker KA, Walter S, Becker JU, Kramer M, Hessler G, Weber S, Göthert JR, Fassbender K, Gulbins E, Carpinteiro A. Beckmann N, et al. Among authors: gothert jr. Cell Physiol Biochem. 2017;43(4):1460-1471. doi: 10.1159/000481968. Epub 2017 Oct 16. Cell Physiol Biochem. 2017. PMID: 29035882 Free article.
Expansion of functional personalized cells with specific transgene combinations.
Lipps C, Klein F, Wahlicht T, Seiffert V, Butueva M, Zauers J, Truschel T, Luckner M, Köster M, MacLeod R, Pezoldt J, Hühn J, Yuan Q, Müller PP, Kempf H, Zweigerdt R, Dittrich-Breiholz O, Pufe T, Beckmann R, Drescher W, Riancho J, Sañudo C, Korff T, Opalka B, Rebmann V, Göthert JR, Alves PM, Ott M, Schucht R, Hauser H, Wirth D, May T. Lipps C, et al. Among authors: gothert jr. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4. Nat Commun. 2018. PMID: 29520052 Free PMC article.
A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit.
Meyer zu Hörste M, Ströher E, Berchner-Pfannschmidt U, Schmitz-Spanke S, Pink M, Göthert JR, Fischer JW, Gulbins E, Eckstein AK. Meyer zu Hörste M, et al. Among authors: gothert jr. J Clin Endocrinol Metab. 2011 Nov;96(11):E1727-36. doi: 10.1210/jc.2011-1156. Epub 2011 Sep 14. J Clin Endocrinol Metab. 2011. PMID: 21917865
Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.
Hasenberg A, Hasenberg M, Männ L, Neumann F, Borkenstein L, Stecher M, Kraus A, Engel DR, Klingberg A, Seddigh P, Abdullah Z, Klebow S, Engelmann S, Reinhold A, Brandau S, Seeling M, Waisman A, Schraven B, Göthert JR, Nimmerjahn F, Gunzer M. Hasenberg A, et al. Among authors: gothert jr. Nat Methods. 2015 May;12(5):445-52. doi: 10.1038/nmeth.3322. Epub 2015 Mar 16. Nat Methods. 2015. PMID: 25775045
Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML.
Solovey M, Wang Y, Michel C, Metzeler KH, Herold T, Göthert JR, Ellenrieder V, Hessmann E, Gattenlöhner S, Neubauer A, Pavlinic D, Benes V, Rupp O, Burchert A. Solovey M, et al. Among authors: gothert jr. J Hematol Oncol. 2019 Jul 8;12(1):72. doi: 10.1186/s13045-019-0765-y. J Hematol Oncol. 2019. PMID: 31286998 Free PMC article.
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.
Nussbaum C, Bannenberg S, Keul P, Gräler MH, Gonçalves-de-Albuquerque CF, Korhonen H, von Wnuck Lipinski K, Heusch G, de Castro Faria Neto HC, Rohwedder I, Göthert JR, Prasad VP, Haufe G, Lange-Sperandio B, Offermanns S, Sperandio M, Levkau B. Nussbaum C, et al. Among authors: gothert jr. Nat Commun. 2015 Apr 2;6:6416. doi: 10.1038/ncomms7416. Nat Commun. 2015. PMID: 25832730 Free PMC article.
53 results