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Endocannabinoid-Binding Receptors as Drug Targets.
Gómez-Cañas M, Rodríguez-Cueto C, Satta V, Hernández-Fisac I, Navarro E, Fernández-Ruiz J. Gómez-Cañas M, et al. Methods Mol Biol. 2023;2576:67-94. doi: 10.1007/978-1-0716-2728-0_6. Methods Mol Biol. 2023. PMID: 36152178
Prospects for cannabinoid therapies in basal ganglia disorders.
Fernández-Ruiz J, Moreno-Martet M, Rodríguez-Cueto C, Palomo-Garo C, Gómez-Cañas M, Valdeolivas S, Guaza C, Romero J, Guzmán M, Mechoulam R, Ramos JA. Fernández-Ruiz J, et al. Br J Pharmacol. 2011 Aug;163(7):1365-78. doi: 10.1111/j.1476-5381.2011.01365.x. Br J Pharmacol. 2011. PMID: 21545415 Free PMC article. Review.
Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis.
Burgaz S, García C, Gonzalo-Consuegra C, Gómez-Almería M, Ruiz-Pino F, Unciti JD, Gómez-Cañas M, Alcalde J, Morales P, Jagerovic N, Rodríguez-Cueto C, de Lago E, Muñoz E, Fernández-Ruiz J. Burgaz S, et al. Among authors: gomez canas m. Molecules. 2021 Dec 16;26(24):7643. doi: 10.3390/molecules26247643. Molecules. 2021. PMID: 34946726 Free PMC article.
Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.
Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ, Sánchez C. Moreno E, et al. J Biol Chem. 2014 Aug 8;289(32):21960-72. doi: 10.1074/jbc.M114.561761. Epub 2014 Jun 18. J Biol Chem. 2014. PMID: 24942731 Free PMC article.
The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways.
del Río C, Navarrete C, Collado JA, Bellido ML, Gómez-Cañas M, Pazos MR, Fernández-Ruiz J, Pollastro F, Appendino G, Calzado MA, Cantarero I, Muñoz E. del Río C, et al. Sci Rep. 2016 Feb 18;6:21703. doi: 10.1038/srep21703. Sci Rep. 2016. PMID: 26887982 Free PMC article.
Δ9 -Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPARγ and CB1 receptors.
Palomares B, Garrido-Rodriguez M, Gonzalo-Consuegra C, Gómez-Cañas M, Saen-Oon S, Soliva R, Collado JA, Fernández-Ruiz J, Morello G, Calzado MA, Appendino G, Muñoz E. Palomares B, et al. Among authors: gomez canas m. Br J Pharmacol. 2020 Sep;177(17):4034-4054. doi: 10.1111/bph.15155. Epub 2020 Jul 8. Br J Pharmacol. 2020. PMID: 32510591 Free PMC article.
Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease.
Sánchez Montero JM, Agis-Torres A, Solano D, Söllhuber M, Fernandez M, Villaro W, Gómez-Cañas M, García-Arencibia M, Fernández-Ruiz J, Egea J, Martín MI, Girón R. Sánchez Montero JM, et al. Among authors: gomez canas m. Eur J Pharmacol. 2021 Mar 15;895:173875. doi: 10.1016/j.ejphar.2021.173875. Epub 2021 Jan 15. Eur J Pharmacol. 2021. PMID: 33460612
Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
Deiana V, Gómez-Cañas M, Pazos MR, Fernández-Ruiz J, Asproni B, Cichero E, Fossa P, Muñoz E, Deligia F, Murineddu G, García-Arencibia M, Pinna GA. Deiana V, et al. Eur J Med Chem. 2016 Apr 13;112:66-80. doi: 10.1016/j.ejmech.2016.02.005. Epub 2016 Feb 6. Eur J Med Chem. 2016. PMID: 26890113
32 results