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Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture.
Luo W, Wang Y, Zhang L, Ren P, Zhang C, Li Y, Azares AR, Zhang M, Guo J, Ghaghada KB, Starosolski ZA, Rajapakshe K, Coarfa C, Li Y, Chen R, Fujiwara K, Abe JI, Coselli JS, Milewicz DM, LeMaire SA, Shen YH. Luo W, et al. Among authors: fujiwara k. Circulation. 2020 Jan 7;141(1):42-66. doi: 10.1161/CIRCULATIONAHA.119.041460. Epub 2019 Dec 30. Circulation. 2020. PMID: 31887080 Free PMC article.
PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation.
Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J. Heo KS, et al. Among authors: fujiwara k. J Cell Biol. 2011 May 30;193(5):867-84. doi: 10.1083/jcb.201010051. J Cell Biol. 2011. PMID: 21624955 Free PMC article.
p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.
Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J. Le NT, et al. Among authors: fujiwara k. Circ Res. 2012 Feb 17;110(4):536-50. doi: 10.1161/CIRCRESAHA.111.254730. Epub 2012 Jan 19. Circ Res. 2012. PMID: 22267842 Free PMC article.
Glucagon-like peptide-1 and its cardiovascular effects.
Heo KS, Fujiwara K, Abe J. Heo KS, et al. Among authors: fujiwara k. Curr Atheroscler Rep. 2012 Oct;14(5):422-8. doi: 10.1007/s11883-012-0265-9. Curr Atheroscler Rep. 2012. PMID: 22878937 Review.
Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.
Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J. Heo KS, et al. Among authors: fujiwara k. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29. Arterioscler Thromb Vasc Biol. 2013. PMID: 23202365 Free PMC article.
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis.
Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. Le NT, et al. Among authors: fujiwara k. Circulation. 2013 Jan 29;127(4):486-99. doi: 10.1161/CIRCULATIONAHA.112.116988. Epub 2012 Dec 14. Circulation. 2013. PMID: 23243209 Free PMC article.
Shear stress and atherosclerosis.
Heo KS, Fujiwara K, Abe J. Heo KS, et al. Among authors: fujiwara k. Mol Cells. 2014 Jun;37(6):435-40. doi: 10.14348/molcells.2014.0078. Epub 2014 Apr 30. Mol Cells. 2014. PMID: 24781409 Free PMC article. Review.
3,425 results