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Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold.
Rong J, Mori W, Xia X, Schafroth MA, Zhao C, Van RS, Yamasaki T, Chen J, Xiao Z, Haider A, Ogasawara D, Hiraishi A, Shao T, Zhang Y, Chen Z, Pang F, Hu K, Xie L, Fujinaga M, Kumata K, Gou Y, Fang Y, Gu S, Wei H, Bao L, Xu H, Collier TL, Shao Y, Carson RE, Cravatt BF, Wang L, Zhang MR, Liang SH. Rong J, et al. Among authors: fujinaga m. J Med Chem. 2021 Oct 14;64(19):14283-14298. doi: 10.1021/acs.jmedchem.1c00747. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34569803 Free PMC article.
Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity.
Yui J, Hatori A, Kawamura K, Yanamoto K, Yamasaki T, Ogawa M, Yoshida Y, Kumata K, Fujinaga M, Nengaki N, Fukumura T, Suzuki K, Zhang MR. Yui J, et al. Among authors: fujinaga m. Neuroimage. 2011 Jan 1;54(1):123-30. doi: 10.1016/j.neuroimage.2010.08.010. Epub 2010 Aug 10. Neuroimage. 2011. PMID: 20705143
Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.
Fujinaga M, Yamasaki T, Kawamura K, Kumata K, Hatori A, Yui J, Yanamoto K, Yoshida Y, Ogawa M, Nengaki N, Maeda J, Fukumura T, Zhang MR. Fujinaga M, et al. Bioorg Med Chem. 2011 Jan 1;19(1):102-10. doi: 10.1016/j.bmc.2010.11.048. Epub 2010 Nov 25. Bioorg Med Chem. 2011. PMID: 21172734
Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 1.
Yamasaki T, Fujinaga M, Yoshida Y, Kumata K, Yui J, Kawamura K, Hatori A, Fukumura T, Zhang MR. Yamasaki T, et al. Among authors: fujinaga m. Bioorg Med Chem Lett. 2011 May 15;21(10):2998-3001. doi: 10.1016/j.bmcl.2011.03.046. Epub 2011 Mar 17. Bioorg Med Chem Lett. 2011. PMID: 21470858
Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo- isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains.
Fujinaga M, Maeda J, Yui J, Hatori A, Yamasaki T, Kawamura K, Kumata K, Yoshida Y, Nagai Y, Higuchi M, Suhara T, Fukumura T, Zhang MR. Fujinaga M, et al. J Neurochem. 2012 Apr;121(1):115-24. doi: 10.1111/j.1471-4159.2011.07348.x. Epub 2011 Jul 1. J Neurochem. 2012. PMID: 21668889 Free article.
Evaluation of the P-glycoprotein- and breast cancer resistance protein-mediated brain penetration of 11C-labeled topotecan using small-animal positron emission tomography.
Yamasaki T, Fujinaga M, Kawamura K, Hatori A, Yui J, Nengaki N, Ogawa M, Yoshida Y, Wakizaka H, Yanamoto K, Fukumura T, Zhang MR. Yamasaki T, et al. Among authors: fujinaga m. Nucl Med Biol. 2011 Jul;38(5):707-14. doi: 10.1016/j.nucmedbio.2010.12.012. Epub 2011 Mar 3. Nucl Med Biol. 2011. PMID: 21718946
Synthesis and evaluation of novel carbon-11 labeled oxopurine analogues for positron emission tomography imaging of translocator protein (18 kDa) in peripheral organs.
Kumata K, Yui J, Hatori A, Fujinaga M, Yanamoto K, Yamasaki T, Kawamura K, Wakizaka H, Nengaki N, Yoshida Y, Ogawa M, Fukumura T, Zhang MR. Kumata K, et al. Among authors: fujinaga m. J Med Chem. 2011 Sep 8;54(17):6040-9. doi: 10.1021/jm200516a. Epub 2011 Aug 4. J Med Chem. 2011. PMID: 21790126
206 results