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Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms.
Cell Rep. 2024 Jan 23;43(1):113608. doi: 10.1016/j.celrep.2023.113608. Epub 2023 Dec 20.
Cell Rep. 2024.
PMID: 38117649
Free PMC article.
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Gleitz HFE, Dugourd AJF, Leimkühler NB, Snoeren IAM, Fuchs SNR, Menzel S, Ziegler S, Kröger N, Triviai I, Büsche G, Kreipe H, Banjanin B, Pritchard JE, Hoogenboezem R, Bindels EM, Schumacher N, Rose-John S, Elf S, Saez-Rodriguez J, Kramann R, Schneider RK.
Gleitz HFE, et al. Among authors: fuchs snr.
Blood. 2020 Oct 29;136(18):2051-2064. doi: 10.1182/blood.2019004095.
Blood. 2020.
PMID: 32726410
Free PMC article.
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Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Leimkühler NB, Gleitz HFE, Ronghui L, Snoeren IAM, Fuchs SNR, Nagai JS, Banjanin B, Lam KH, Vogl T, Kuppe C, Stalmann USA, Büsche G, Kreipe H, Gütgemann I, Krebs P, Banz Y, Boor P, Tai EW, Brümmendorf TH, Koschmieder S, Crysandt M, Bindels E, Kramann R, Costa IG, Schneider RK.
Leimkühler NB, et al. Among authors: fuchs snr.
Cell Stem Cell. 2021 Apr 1;28(4):637-652.e8. doi: 10.1016/j.stem.2020.11.004. Epub 2020 Dec 9.
Cell Stem Cell. 2021.
PMID: 33301706
Free PMC article.
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Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing.
Gleitz HFE, Snoeren IAM, Fuchs SNR, Leimkühler NB, Schneider RK.
Gleitz HFE, et al. Among authors: fuchs snr.
STAR Protoc. 2021 May 12;2(2):100538. doi: 10.1016/j.xpro.2021.100538. eCollection 2021 Jun 18.
STAR Protoc. 2021.
PMID: 34027494
Free PMC article.
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Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion.
Stalmann USA, Ticconi F, Snoeren IAM, Li R, Gleitz HFE, Cowley GS, McConkey ME, Wong AB, Schmitz S, Fuchs SNR, Sood S, Leimkühler NB, Martinez-Høyer S, Banjanin B, Root D, Brümmendorf TH, Pearce JE, Schuppert A, Bindels EMJ, Essers MA, Heckl D, Stiehl T, Costa IG, Ebert BL, Schneider RK.
Stalmann USA, et al. Among authors: fuchs snr.
Blood Adv. 2022 Mar 22;6(6):1780-1796. doi: 10.1182/bloodadvances.2021006061.
Blood Adv. 2022.
PMID: 35016204
Free PMC article.
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Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation.
Fuchs SNR, Stalmann USA, Snoeren IAM, Bindels E, Schmitz S, Banjanin B, Hoogenboezem RM, van Herk S, Saad M, Walter W, Haferlach T, Seillier L, Saez-Rodriguez J, Dugourd AJF, Lehmann KV, Ben-Neriah Y, Gleitz HFE, Schneider RK.
Fuchs SNR, et al.
Blood Adv. 2024 Feb 13;8(3):766-779. doi: 10.1182/bloodadvances.2022008926.
Blood Adv. 2024.
PMID: 38147624
Free PMC article.
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