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Page 1
Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.
Musiu C, Caligola S, Fiore A, Lamolinara A, Frusteri C, Del Pizzo FD, De Sanctis F, Canè S, Adamo A, Hofer F, Barouni RM, Grilli A, Zilio S, Serafini P, Tacconelli E, Donadello K, Gottin L, Polati E, Girelli D, Polidoro I, Iezzi PA, Angelucci D, Capece A, Chen Y, Shi ZL, Murray PJ, Chilosi M, Amit I, Bicciato S, Iezzi M, Bronte V, Ugel S. Musiu C, et al. Among authors: frusteri c. Cell Death Differ. 2022 Feb;29(2):420-438. doi: 10.1038/s41418-021-00866-0. Epub 2021 Sep 13. Cell Death Differ. 2022. PMID: 34518653 Free PMC article.
Moonlighting Proteins Are Important Players in Cancer Immunology.
Adamo A, Frusteri C, Pallotta MT, Pirali T, Sartoris S, Ugel S. Adamo A, et al. Among authors: frusteri c. Front Immunol. 2021 Jan 18;11:613069. doi: 10.3389/fimmu.2020.613069. eCollection 2020. Front Immunol. 2021. PMID: 33584695 Free PMC article. Review.
Arginase 1-Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti-PD-1 Checkpoint Blockade.
Aaboe Jørgensen M, Ugel S, Linder Hübbe M, Carretta M, Perez-Penco M, Weis-Banke SE, Martinenaite E, Kopp K, Chapellier M, Adamo A, De Sanctis F, Frusteri C, Iezzi M, Zocca MB, Hargbøll Madsen D, Wakatsuki Pedersen A, Bronte V, Andersen MH. Aaboe Jørgensen M, et al. Among authors: frusteri c. Cancer Immunol Res. 2021 Nov;9(11):1316-1326. doi: 10.1158/2326-6066.CIR-21-0280. Epub 2021 Sep 13. Cancer Immunol Res. 2021. PMID: 34518197
Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer.
De Sanctis F, Lamolinara A, Boschi F, Musiu C, Caligola S, Trovato R, Fiore A, Frusteri C, Anselmi C, Poffe O, Cestari T, Canè S, Sartoris S, Giugno R, Del Rosario G, Zappacosta B, Del Pizzo F, Fassan M, Dugnani E, Piemonti L, Bottani E, Decimo I, Paiella S, Salvia R, Lawlor RT, Corbo V, Park Y, Tuveson DA, Bassi C, Scarpa A, Iezzi M, Ugel S, Bronte V. De Sanctis F, et al. Among authors: frusteri c. J Immunother Cancer. 2022 Jan;10(1):e003549. doi: 10.1136/jitc-2021-003549. J Immunother Cancer. 2022. PMID: 35022194 Free PMC article.
p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.
Salemme V, Vedelago M, Sarcinella A, Moietta F, Piccolantonio A, Moiso E, Centonze G, Manco M, Guala A, Lamolinara A, Angelini C, Morellato A, Natalini D, Calogero R, Incarnato D, Oliviero S, Conti L, Iezzi M, Tosoni D, Bertalot G, Freddi S, Tucci FA, De Sanctis F, Frusteri C, Ugel S, Bronte V, Cavallo F, Provero P, Gai M, Taverna D, Turco E, Pece S, Defilippi P. Salemme V, et al. Among authors: frusteri c. Nat Commun. 2023 May 11;14(1):2350. doi: 10.1038/s41467-023-37824-y. Nat Commun. 2023. PMID: 37169737 Free PMC article.
Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patients.
Adamo A, Frusteri C, Pilotto S, Caligola S, Belluomini L, Poffe O, Giacobazzi L, Dusi S, Musiu C, Hu Y, Wang T, Rizzini D, Vella A, Canè S, Sartori G, Insolda J, Sposito M, Incani UC, Carbone C, Piro G, Pettinella F, Qi F, Wang D, Sartoris S, De Sanctis F, Scapini P, Dusi S, Cassatella MA, Bria E, Milella M, Bronte V, Ugel S. Adamo A, et al. Among authors: frusteri c. Oncoimmunology. 2023 Sep 14;12(1):2253644. doi: 10.1080/2162402X.2023.2253644. eCollection 2023. Oncoimmunology. 2023. PMID: 37720688 Free PMC article.
Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease.
Alfen JS, Larghi P, Facciotti F, Gagliani N, Bosotti R, Paroni M, Maglie S, Gruarin P, Vasco CM, Ranzani V, Frusteri C, Iseppon A, Moro M, Crosti MC, Gatti S, Pagani M, Caprioli F, Abrignani S, Flavell RA, Geginat J. Alfen JS, et al. Among authors: frusteri c. J Allergy Clin Immunol. 2018 Nov;142(5):1537-1547.e8. doi: 10.1016/j.jaci.2017.12.984. Epub 2018 Jan 31. J Allergy Clin Immunol. 2018. PMID: 29369775 Free article.
Widespread in vivo efficacy of The-0504: A conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers.
Fracasso G, Falvo E, Tisci G, Sala G, Colotti G, Cingarlini S, Tito C, Bibbo S, Frusteri C, Tremante E, Giordani E, Giacomini P, Ceci P. Fracasso G, et al. Among authors: frusteri c. Heliyon. 2023 Oct 6;9(10):e20770. doi: 10.1016/j.heliyon.2023.e20770. eCollection 2023 Oct. Heliyon. 2023. PMID: 37860543 Free PMC article.
Decreased apoptotic priming and loss of BCL-2 dependence are functional hallmarks of Richter's syndrome.
Rigo A, Vaisitti T, Laudanna C, Terrabuio E, Micillo M, Frusteri C, D'Ulivo B, Merigo F, Sbarbati A, Mellert K, Möeller P, Montresor A, Di Napoli A, Cirombella R, Butturini E, Massaia M, Constantin G, Vinante F, Deaglio S, Ferrarini I. Rigo A, et al. Among authors: frusteri c. Cell Death Dis. 2024 May 9;15(5):323. doi: 10.1038/s41419-024-06707-5. Cell Death Dis. 2024. PMID: 38724507 Free PMC article.
Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC.
Lupo F, Pezzini F, Pasini D, Fiorini E, Adamo A, Veghini L, Bevere M, Frusteri C, Delfino P, D'agosto S, Andreani S, Piro G, Malinova A, Wang T, De Sanctis F, Lawlor RT, Hwang CI, Carbone C, Amelio I, Bailey P, Bronte V, Tuveson D, Scarpa A, Ugel S, Corbo V. Lupo F, et al. Among authors: frusteri c. Gut. 2024 Apr 26:gutjnl-2023-329807. doi: 10.1136/gutjnl-2023-329807. Online ahead of print. Gut. 2024. PMID: 38670629 Free article.