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The serotonin receptor 3E variant is a risk factor for female IBS-D.
Fritz N, Berens S, Dong Y, Martínez C, Schmitteckert S, Houghton LA, Goebel-Stengel M, Wahl V, Kabisch M, Götze D, D'Amato M, Zheng T, Röth R, Mönnikes H, Tesarz J, Engel F, Gauss A, Raithel M, Andresen V, Keller J, Frieling T, Pehl C, Stein-Thöringer C, Clarke G, Kennedy PJ, Cryan JF, Dinan TG, Quigley EMM, Spiller R, Beltrán C, Madrid AM, Torres V, Mayer EA, Sayuk G, Gazouli M, Karamanolis G, Bustamante M, Estivil X, Rabionet R, Hoffmann P, Nöthen MM, Heilmann-Heimbach S, Schmidt B, Franke A, Lieb W, Herzog W, Boeckxstaens G, Wouters MM, Simrén M, Rappold GA, Vicario M, Santos J, Schaefert R, Lorenzo-Bermejo J, Niesler B. Fritz N, et al. Among authors: frieling t. J Mol Med (Berl). 2022 Nov;100(11):1617-1627. doi: 10.1007/s00109-022-02244-w. Epub 2022 Sep 19. J Mol Med (Berl). 2022. PMID: 36121467 Free PMC article.
Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFα, and Tryptase (IBS-Cocktail).
Ostertag D, Buhner S, Michel K, Pehl C, Kurjak M, Götzberger M, Schulte-Frohlinde E, Frieling T, Enck P, Phillip J, Schemann M. Ostertag D, et al. Among authors: frieling t. Front Neurosci. 2015 Dec 16;9:465. doi: 10.3389/fnins.2015.00465. eCollection 2015. Front Neurosci. 2015. PMID: 26733780 Free PMC article.
Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients.
Buhner S, Hahne H, Hartwig K, Li Q, Vignali S, Ostertag D, Meng C, Hörmannsperger G, Braak B, Pehl C, Frieling T, Barbara G, De Giorgio R, Demir IE, Ceyhan GO, Zeller F, Boeckxstaens G, Haller D, Kuster B, Schemann M. Buhner S, et al. Among authors: frieling t. PLoS One. 2018 Mar 12;13(3):e0193943. doi: 10.1371/journal.pone.0193943. eCollection 2018. PLoS One. 2018. PMID: 29529042 Free PMC article.
The Diagnosis and Treatment of Functional Dyspepsia.
Madisch A, Andresen V, Enck P, Labenz J, Frieling T, Schemann M. Madisch A, et al. Among authors: frieling t. Dtsch Arztebl Int. 2018 Mar 30;115(13):222-232. doi: 10.3238/arztebl.2018.0222. Dtsch Arztebl Int. 2018. PMID: 29669681 Free PMC article.
[Interpretation und performance of high-resolution esophageal manometry: Recommendations of the German Association of Neurogastroenterology and Motility (DGNM) and the German Association of Gastroenterology, Digestive and Metabolic Diseases (DGVS)].
Keller J, Fox MR, Allescher HD, Frieling T, Fuchs KH, Goebel-Stengel M, Pehl C, Schirra J, van der Voort I, Storr M. Keller J, et al. Among authors: frieling t. Z Gastroenterol. 2018 Nov;56(11):1378-1408. doi: 10.1055/a-0713-0944. Epub 2018 Nov 12. Z Gastroenterol. 2018. PMID: 30419581 German.
The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome.
Mohr S, Fritz N, Hammer C, Martínez C, Berens S, Schmitteckert S, Wahl V, Schmidt M, Houghton LA, Goebel-Stengel M, Kabisch M, Götze D, Milovač I, D'Amato M, Zheng T, Röth R, Mönnikes H, Engel F, Gauss A, Tesarz J, Raithel M, Andresen V, Frieling T, Keller J, Pehl C, Stein-Thöringer C, Clarke G, Kennedy PJ, Cryan JF, Dinan TG, Quigley EMM, Spiller R, Beltrán C, Madrid AM, Torres V, Pérez de Arce E, Herzog W, Mayer EA, Sayuk G, Gazouli M, Karamanolis G, Kapur-Pojskič L, Bustamante M, Rabionet R, Estivil X, Franke A, Lieb W, Boeckxstaens G, Wouters MM, Simrén M, Rappold GA, Vicario M, Santos J, Schaefert R, Lorenzo-Bermejo J, Niesler B. Mohr S, et al. Among authors: frieling t. J Cell Mol Med. 2021 Aug;25(16):8047-8061. doi: 10.1111/jcmm.16736. Epub 2021 Jun 24. J Cell Mol Med. 2021. PMID: 34165249 Free PMC article.
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S; 23andMe Research Team; Voda AI; Bellygenes Initiative; Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Eijsbouts C, et al. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 5. Nat Genet. 2021. PMID: 34741163 Free PMC article.
Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM) – Juni 2021 – AWMF-Registriernummer: 021/016.
Layer P, Andresen V, Allescher H, Bischoff SC, Claßen M, Elsenbruch S, Freitag M, Frieling T, Gebhard M, Goebel-Stengel M, Häuser W, Holtmann G, Keller J, Kreis ME, Kruis W, Langhorst J, Jansen PL, Madisch A, Mönnikes H, Müller-Lissner S, Niesler B, Pehl C, Pohl D, Raithel M, Röhrig-Herzog G, Schemann M, Schmiedel S, Schwille-Kiuntke J, Storr M, Preiß JC; Collaborators:; Andus T, Buderus S, Ehlert U, Engel M, Enninger A, Fischbach W, Gillessen A, Gschossmann J, Gundling F, Haag S, Helwig U, Hollerbach S, Karaus M, Katschinski M, Krammer H, Kuhlbusch-Zicklam R, Matthes H, Menge D, Miehlke S, Posovszky MC, Schaefert R, Schmidt-Choudhury A, Schwandner O, Schweinlin A, Seidl H, Stengel A, Tesarz J, van der Voort I, Voderholzer W, von Boyen G, von Schönfeld J, Wedel T; in Zusammenarbeit mit:; Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM); Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI); Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV); Deutsche Gesellschaft für Ernährungsmedizin (DGEM); Deutsche Gesellschaft für Geriatrie (DGG); Deutsche Gesellschaft für Innere Medizin (DGIM); Deutsche Gesellschaft für Naturheilk… See abstract for full author list ➔ Layer P, et al. Among authors: frieling t. Z Gastroenterol. 2021 Dec;59(12):1323-1415. doi: 10.1055/a-1591-4794. Epub 2021 Dec 10. Z Gastroenterol. 2021. PMID: 34891206 Free article. German. No abstract available.
[Anorectal manometry].
Pehl C, Enck P, Franke A, Frieling T, Heitland W, Herold A, Hinninghofen H, Karaus M, Keller J, Krammer HJ, Kreis M, Kuhlbusch-Zicklam R, Mönnikes H, Münnich U, Schiedeck T, Schmidtmann M; German Society for Neurogastroenterology and Motility; Commission Proctology of the German Society for Digestive and Metabolic Diseases; German Society for Coloprotology; Surgical Working Group Coloproctology of the German Society for Visceral Surgery on Anorectal Manometry in Adults. Pehl C, et al. Among authors: frieling t. Z Gastroenterol. 2007 May;45(5):397-417. doi: 10.1055/s-2007-963099. Z Gastroenterol. 2007. PMID: 17503320 German.
213 results