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A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Maruggi G, Mallett CP, Westerbeck JW, Chen T, Lofano G, Friedrich K, Qu L, Sun JT, McAuliffe J, Kanitkar A, Arrildt KT, Wang KF, McBee I, McCoy D, Terry R, Rowles A, Abrahim MA, Ringenberg MA, Gains MJ, Spickler C, Xie X, Zou J, Shi PY, Dutt T, Henao-Tamayo M, Ragan I, Bowen RA, Johnson R, Nuti S, Luisi K, Ulmer JB, Steff AM, Jalah R, Bertholet S, Stokes AH, Yu D. Maruggi G, et al. Among authors: friedrich k. Mol Ther. 2022 May 4;30(5):1897-1912. doi: 10.1016/j.ymthe.2022.01.001. Epub 2022 Jan 3. Mol Ther. 2022. PMID: 34990810 Free PMC article. Clinical Trial.
Formulation Design, Optimization and In Vivo Evaluations of an α-Tocopherol-Containing Self-Emulsified Adjuvant System using Inactivated Influenza Vaccine.
Lodaya RN, Kanitkar AP, Friedrich K, Henson D, Yamagata R, Nuti S, Mallett CP, Bertholet S, Amiji MM, O'Hagan DT. Lodaya RN, et al. Among authors: friedrich k. J Control Release. 2019 Dec 28;316:12-21. doi: 10.1016/j.jconrel.2019.10.042. Epub 2019 Oct 31. J Control Release. 2019. PMID: 31678654 Free article.
Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F.
Harshbarger W, Tian S, Wahome N, Balsaraf A, Bhattacharya D, Jiang D, Pandey R, Tungare K, Friedrich K, Mehzabeen N, Biancucci M, Chinchilla-Olszar D, Mallett CP, Huang Y, Wang Z, Bottomley MJ, Malito E, Chandramouli S. Harshbarger W, et al. Among authors: friedrich k. PLoS Pathog. 2020 Nov 2;16(11):e1008943. doi: 10.1371/journal.ppat.1008943. eCollection 2020 Nov. PLoS Pathog. 2020. PMID: 33137810 Free PMC article.
Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant.
Wen Y, Trinh HV, Linton CE, Tani C, Norais N, Martinez-Guzman D, Ramesh P, Sun Y, Situ F, Karaca-Griffin S, Hamlin C, Onkar S, Tian S, Hilt S, Malyala P, Lodaya R, Li N, Otten G, Palladino G, Friedrich K, Aggarwal Y, LaBranche C, Duffy R, Shen X, Tomaras GD, Montefiori DC, Fulp W, Gottardo R, Burke B, Ulmer JB, Zolla-Pazner S, Liao HX, Haynes BF, Michael NL, Kim JH, Rao M, O'Connell RJ, Carfi A, Barnett SW. Wen Y, et al. Among authors: friedrich k. PLoS One. 2018 Apr 26;13(4):e0194266. doi: 10.1371/journal.pone.0194266. eCollection 2018. PLoS One. 2018. PMID: 29698406 Free PMC article.
Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies.
Ciferri C, Chandramouli S, Leitner A, Donnarumma D, Cianfrocco MA, Gerrein R, Friedrich K, Aggarwal Y, Palladino G, Aebersold R, Norais N, Settembre EC, Carfi A. Ciferri C, et al. Among authors: friedrich k. PLoS Pathog. 2015 Oct 20;11(10):e1005230. doi: 10.1371/journal.ppat.1005230. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26485028 Free PMC article.
Expression of CD39 is associated with T cell exhaustion in ovarian cancer and its blockade reverts T cell dysfunction.
Marius W, Leticia OF, Friedrich KN, Stephan M, Louisa H, Tabea S, Elisa S, Pauline W, Yi D, Qi M, Barbara S, Carsten B, Walter F, Jasmin W, Franziska B. Marius W, et al. Among authors: friedrich kn. Oncoimmunology. 2024 May 9;13(1):2346359. doi: 10.1080/2162402X.2024.2346359. eCollection 2024. Oncoimmunology. 2024. PMID: 38737794 Free PMC article.
Circoviridae Survey in Captive Non-Human Primates, Italy.
Sarchese V, Di Profio F, Palombieri A, Friedrich KG, Robetto S, Banyai K, Marsilio F, Martella V, Di Martino B. Sarchese V, et al. Among authors: friedrich kg. Animals (Basel). 2024 Mar 13;14(6):881. doi: 10.3390/ani14060881. Animals (Basel). 2024. PMID: 38539979 Free PMC article.
424 results