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Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M. Moschandrea C, et al. Among authors: frezza c. Nature. 2024 Jan;625(7994):385-392. doi: 10.1038/s41586-023-06857-0. Epub 2023 Dec 20. Nature. 2024. PMID: 38123683 Free PMC article.
Fumarate hydratase in cancer: A multifaceted tumour suppressor.
Schmidt C, Sciacovelli M, Frezza C. Schmidt C, et al. Among authors: frezza c. Semin Cell Dev Biol. 2020 Feb;98:15-25. doi: 10.1016/j.semcdb.2019.05.002. Epub 2019 May 22. Semin Cell Dev Biol. 2020. PMID: 31085323 Free PMC article. Review.
Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation.
Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MM, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K, Murphy MP. Martin JL, et al. Among authors: frezza c. Nat Metab. 2019 Sep 30;1:966-974. doi: 10.1038/s42255-019-0115-y. Nat Metab. 2019. PMID: 32395697 Free PMC article.
Convergent somatic mutations in metabolism genes in chronic liver disease.
Ng SWK, Rouhani FJ, Brunner SF, Brzozowska N, Aitken SJ, Yang M, Abascal F, Moore L, Nikitopoulou E, Chappell L, Leongamornlert D, Ivovic A, Robinson P, Butler T, Sanders MA, Williams N, Coorens THH, Teague J, Raine K, Butler AP, Hooks Y, Wilson B, Birtchnell N, Naylor H, Davies SE, Stratton MR, Martincorena I, Rahbari R, Frezza C, Hoare M, Campbell PJ. Ng SWK, et al. Among authors: frezza c. Nature. 2021 Oct;598(7881):473-478. doi: 10.1038/s41586-021-03974-6. Epub 2021 Oct 13. Nature. 2021. PMID: 34646017
Lung Tumor Growth Promotion by Tobacco-Specific Nitrosamines Involves the β2-Adrenergic Receptors-Dependent Stimulation of Mitochondrial REDOX Signaling.
Sarlak S, Lalou C, Sant'Anna-Silva ACB, Mafhouf W, De Luise M, Rousseau B, Izotte J, Claverol S, Lacombe D, Nikitopoulou E, Yang M, Oliveira M, Frezza C, Gasparre G, Rezvani HR, Amoedo ND, Rossignol R. Sarlak S, et al. Among authors: frezza c. Antioxid Redox Signal. 2022 Mar;36(7-9):525-549. doi: 10.1089/ars.2020.8259. Antioxid Redox Signal. 2022. PMID: 34715750
Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells.
Harris R, Yang M, Schmidt C, Royet C, Singh S, Natarajan A, Morris M, Frezza C, Laman H. Harris R, et al. Among authors: frezza c. J Cell Biol. 2022 Jul 4;221(7):e202203095. doi: 10.1083/jcb.202203095. Epub 2022 Jun 7. J Cell Biol. 2022. PMID: 35670764 Free PMC article.
HIRA loss transforms FH-deficient cells.
Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Valcarcel-Jimenez L, et al. Among authors: frezza c. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269833 Free PMC article.
232 results