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A biallelic loss-of-function variant in MYZAP is associated with a recessive form of severe dilated cardiomyopathy.
Maver A, Zigman T, Rangrez AY, Coric M, Homolak J, Saric D, Skific I, Udovicic M, Zekusic M, Saleem U, Laufer SD, Hansen A, Frey N, Baric I, Peterlin B. Maver A, et al. Among authors: frey n. Cold Spring Harb Mol Case Stud. 2022 Jul 15;8(5):a006221. doi: 10.1101/mcs.a006221. Online ahead of print. Cold Spring Harb Mol Case Stud. 2022. PMID: 35840178 Free PMC article.
Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling.
Rangrez AY, Eden M, Poyanmehr R, Kuhn C, Stiebeling K, Dierck F, Bernt A, Lüllmann-Rauch R, Weiler H, Kirchof P, Frank D, Frey N. Rangrez AY, et al. Among authors: frey n. J Biol Chem. 2016 Feb 19;291(8):4128-43. doi: 10.1074/jbc.M115.689620. Epub 2015 Dec 30. J Biol Chem. 2016. PMID: 26719331 Free PMC article.
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.
Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M; German Mouse Clinic Consortium; Hrabě de Angelis M, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N. Eden M, et al. Among authors: frey n. Nat Commun. 2016 Apr 28;7:11317. doi: 10.1315/11317. Nat Commun. 2016. PMID: 27122098 Free PMC article.
MicroRNA miR-301a is a novel cardiac regulator of Cofilin-2.
Rangrez AY, Hoppe P, Kuhn C, Zille E, Frank J, Frey N, Frank D. Rangrez AY, et al. Among authors: frey n. PLoS One. 2017 Sep 8;12(9):e0183901. doi: 10.1371/journal.pone.0183901. eCollection 2017. PLoS One. 2017. PMID: 28886070 Free PMC article.
751 results