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CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids.
Buck TM, Quinn PMJ, Pellissier LP, Mulder AA, Jongejan A, Lu X, Boon N, Koot D, Almushattat H, Arendzen CH, Vos RM, Bradley EJ, Freund C, Mikkers HMM, Boon CJF, Moerland PD, Baas F, Koster AJ, Neefjes J, Berlin I, Jost CR, Wijnholds J. Buck TM, et al. Among authors: freund c. Stem Cell Reports. 2023 Sep 12;18(9):1793-1810. doi: 10.1016/j.stemcr.2023.07.001. Epub 2023 Aug 3. Stem Cell Reports. 2023. PMID: 37541258 Free PMC article.
AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype.
Boon N, Lu X, Andriessen CA, Moustakas I, Buck TM, Freund C, Arendzen CH, Böhringer S, Boon CJF, Mei H, Wijnholds J. Boon N, et al. Among authors: freund c. Stem Cell Reports. 2023 Jun 13;18(6):1388. doi: 10.1016/j.stemcr.2023.05.008. Stem Cell Reports. 2023. PMID: 37315526 Free PMC article. No abstract available.
Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay.
Overeem AW, Chang YW, Moustakas I, Roelse CM, Hillenius S, Helm TV, Schrier VFV, Gonçalves MAFV, Mei H, Freund C, Chuva de Sousa Lopes SM. Overeem AW, et al. Among authors: freund c. Cell Rep Methods. 2023 May 23;3(6):100488. doi: 10.1016/j.crmeth.2023.100488. eCollection 2023 Jun 26. Cell Rep Methods. 2023. PMID: 37426764 Free PMC article.
Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products.
Novoa JJ, Westra IM, Steeneveld E, Fonseca Neves N, Arendzen CH, Rajaei B, Grundeken E, Yildiz M, van der Valk W, Salvador A, Carlotti F, Dijkers PF, Locher H, van den Berg CW, Raymond KI, Kirkeby A, Mummery CL, Rabelink TJ, Freund C, Meij P, Wieles B. Novoa JJ, et al. Among authors: freund c. Cytotherapy. 2024 Mar 5:S1465-3249(24)00070-7. doi: 10.1016/j.jcyt.2024.02.021. Online ahead of print. Cytotherapy. 2024. PMID: 38483359 Free article.
Human iPSC-derived preclinical models to identify toxicity of tumor-specific T cells with clinical potential.
van Amerongen RA, Morton LT, Chaudhari UG, Remst DFG, Hagedoorn RS, van den Berg CW, Freund C, Falkenburg JHF, Heemskerk MHM. van Amerongen RA, et al. Among authors: freund c. Mol Ther Methods Clin Dev. 2023 Jan 20;28:249-261. doi: 10.1016/j.omtm.2023.01.005. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2023. PMID: 36816758 Free PMC article.
Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system.
Novoa J, Westra I, Steeneveld E, Neves NF, Daleman L, Asensio AB, Davis RP, Carlotti F, Freund C, Rabelink T, Meij P, Wieles B. Novoa J, et al. Among authors: freund c. Cytotherapy. 2024 Apr 14:S1465-3249(24)00610-8. doi: 10.1016/j.jcyt.2024.04.004. Online ahead of print. Cytotherapy. 2024. PMID: 38703154 Free article.
269 results