Freudenthal BD - Search Results

1

Oxidative guanine base damage regulates human telomerase activity.

Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL. Fouquerel E, et al. Among authors: freudenthal bd. Nat Struct Mol Biol. 2016 Dec;23(12):1092-1100. doi: 10.1038/nsmb.3319. Epub 2016 Nov 7. Nat Struct Mol Biol. 2016. PMID: 27820808 Free PMC article.

2

Base excision repair of oxidative DNA damage: from mechanism to disease.

Whitaker AM, Schaich MA, Smith MR, Flynn TS, Freudenthal BD. Whitaker AM, et al. Among authors: freudenthal bd. Front Biosci (Landmark Ed). 2017 Mar 1;22(9):1493-1522. doi: 10.2741/4555. Front Biosci (Landmark Ed). 2017. PMID: 28199214 Free PMC article. Review.

3

Mechanisms of nucleotide selection by telomerase.

Schaich MA, Sanford SL, Welfer GA, Johnson SA, Khoang TH, Opresko PL, Freudenthal BD. Schaich MA, et al. Among authors: freudenthal bd. Elife. 2020 Jun 5;9:e55438. doi: 10.7554/eLife.55438. Elife. 2020. PMID: 32501800 Free PMC article.

4

Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs.

Sanford SL, Welfer GA, Freudenthal BD, Opresko PL. Sanford SL, et al. Among authors: freudenthal bd. Nat Commun. 2020 Oct 20;11(1):5288. doi: 10.1038/s41467-020-19115-y. Nat Commun. 2020. PMID: 33082336 Free PMC article.

5

How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle.

Sanford SL, Welfer GA, Freudenthal BD, Opresko PL. Sanford SL, et al. Among authors: freudenthal bd. DNA Repair (Amst). 2021 Nov;107:103198. doi: 10.1016/j.dnarep.2021.103198. Epub 2021 Jul 31. DNA Repair (Amst). 2021. PMID: 34371388 Free PMC article.

6

Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants.

Welfer GA, Borin VA, Cortez LM, Opresko PL, Agarwal PK, Freudenthal BD. Welfer GA, et al. Among authors: freudenthal bd. Genes (Basel). 2023 Jan 21;14(2):281. doi: 10.3390/genes14020281. Genes (Basel). 2023. PMID: 36833208 Free PMC article.

7

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.

Freudenthal BD, Gakhar L, Ramaswamy S, Washington MT. Freudenthal BD, et al. Nat Struct Mol Biol. 2010 Apr;17(4):479-84. doi: 10.1038/nsmb.1776. Epub 2010 Mar 21. Nat Struct Mol Biol. 2010. PMID: 20305653 Free PMC article.

8

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.

Freudenthal BD, Beard WA, Perera L, Shock DD, Kim T, Schlick T, Wilson SH. Freudenthal BD, et al. Nature. 2015 Jan 29;517(7536):635-9. doi: 10.1038/nature13886. Epub 2014 Nov 17. Nature. 2015. PMID: 25409153 Free PMC article.

9

Capturing snapshots of APE1 processing DNA damage.

Freudenthal BD, Beard WA, Cuneo MJ, Dyrkheeva NS, Wilson SH. Freudenthal BD, et al. Nat Struct Mol Biol. 2015 Nov;22(11):924-31. doi: 10.1038/nsmb.3105. Epub 2015 Oct 12. Nat Struct Mol Biol. 2015. PMID: 26458045 Free PMC article.

10

Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.

Whitaker AM, Smith MR, Schaich MA, Freudenthal BD. Whitaker AM, et al. Among authors: freudenthal bd. Nucleic Acids Res. 2017 Jun 20;45(11):6934-6944. doi: 10.1093/nar/gkx293. Nucleic Acids Res. 2017. PMID: 28449123 Free PMC article.

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