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IL-34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis.
Freuchet A, Salama A, Bézie S, Tesson L, Rémy S, Humeau R, Règue H, Sérazin C, Flippe L, Peterson P, Vimond N, Usal C, Ménoret S, Heslan JM, Duteille F, Blanchard F, Giral M, Colonna M, Anegon I, Guillonneau C. Freuchet A, et al. Clin Transl Med. 2022 Aug;12(8):e988. doi: 10.1002/ctm2.988. Clin Transl Med. 2022. PMID: 36030499 Free PMC article.
Transient antibody targeting of CD45RC inhibits the development of graft-versus-host disease.
Boucault L, Lopez Robles MD, Thiolat A, Bézie S, Schmueck-Henneresse M, Braudeau C, Vimond N, Freuchet A, Autrusseau E, Charlotte F, Redjoul R, Beckerich F, Leclerc M, Piaggio E, Josien R, Volk HD, Maury S, Cohen JL, Anegon I, Guillonneau C. Boucault L, et al. Among authors: freuchet a. Blood Adv. 2020 Jun 9;4(11):2501-2515. doi: 10.1182/bloodadvances.2020001688. Blood Adv. 2020. PMID: 32511714 Free PMC article.
Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells.
Freuchet A, Roy P, Armstrong SS, Oliaeimotlagh M, Kumar S, Orecchioni M, Ali AJ, Khan A, Makings J, Lyu Q, Winkels H, Wang E, Durant C, Ghosheh Y, Gulati R, Nettersheim F, Ley K. Freuchet A, et al. Nat Immunol. 2023 Oct;24(10):1748-1761. doi: 10.1038/s41590-023-01589-9. Epub 2023 Aug 10. Nat Immunol. 2023. PMID: 37563308
Sex Differences in Coronary Artery Disease and Diabetes Revealed by scRNA-Seq and CITE-Seq of Human CD4+ T Cells.
Saigusa R, Vallejo J, Gulati R, Suthahar SSA, Suryawanshi V, Alimadadi A, Makings J, Durant CP, Freuchet A, Roy P, Ghosheh Y, Pandori W, Pattarabanjird T, Drago F, Taylor A, McNamara CA, Shemesh A, Lanier LL, Hedrick CC, Ley K. Saigusa R, et al. Among authors: freuchet a. Int J Mol Sci. 2022 Aug 30;23(17):9875. doi: 10.3390/ijms23179875. Int J Mol Sci. 2022. PMID: 36077273 Free PMC article.
Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease.
Saigusa R, Roy P, Freuchet A, Gulati R, Ghosheh Y, Suthahar SSA, Durant CP, Hanna DB, Kiosses WB, Orecchioni M, Wen L, Wu R, Kuniholm MH, Landay AL, Anastos K, Tien PC, Gange SJ, Kassaye S, Vallejo J, Hedrick CC, Kwok WW, Sette A, Hodis HN, Kaplan RC, Ley K. Saigusa R, et al. Among authors: freuchet a. Nat Cardiovasc Res. 2022 May;1(5):462-475. doi: 10.1038/s44161-022-00063-3. Epub 2022 May 12. Nat Cardiovasc Res. 2022. PMID: 35990517 Free PMC article.