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443 results

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Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD. Gubin MM, et al. Among authors: freeman gj. Nature. 2014 Nov 27;515(7528):577-81. doi: 10.1038/nature13988. Nature. 2014. PMID: 25428507 Free PMC article.
CD48-deficient mice have a pronounced defect in CD4(+) T cell activation.
González-Cabrero J, Wise CJ, Latchman Y, Freeman GJ, Sharpe AH, Reiser H. González-Cabrero J, et al. Among authors: freeman gj. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1019-23. doi: 10.1073/pnas.96.3.1019. Proc Natl Acad Sci U S A. 1999. PMID: 9927686 Free PMC article.
PD-L2 is a second ligand for PD-1 and inhibits T cell activation.
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: freeman gj. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527
B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.
Mandelbrot DA, Oosterwegel MA, Shimizu K, Yamada A, Freeman GJ, Mitchell RN, Sayegh MH, Sharpe AH. Mandelbrot DA, et al. Among authors: freeman gj. J Clin Invest. 2001 Apr;107(7):881-7. doi: 10.1172/JCI11710. J Clin Invest. 2001. PMID: 11285307 Free PMC article.
ICOS is critical for CD40-mediated antibody class switching.
McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, Freeman GJ, Sharpe AH. McAdam AJ, et al. Among authors: freeman gj. Nature. 2001 Jan 4;409(6816):102-5. doi: 10.1038/35051107. Nature. 2001. PMID: 11343122
443 results