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Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans.
Yates KB, Tonnerre P, Martin GE, Gerdemann U, Al Abosy R, Comstock DE, Weiss SA, Wolski D, Tully DC, Chung RT, Allen TM, Kim AY, Fidler S, Fox J, Frater J, Lauer GM, Haining WN, Sen DR. Yates KB, et al. Among authors: frater j. Nat Immunol. 2021 Aug;22(8):1020-1029. doi: 10.1038/s41590-021-00979-1. Epub 2021 Jul 26. Nat Immunol. 2021. PMID: 34312547 Free PMC article. Clinical Trial.
Adaptation of HIV-1 to human leukocyte antigen class I.
Kawashima Y, Pfafferott K, Frater J, Matthews P, Payne R, Addo M, Gatanaga H, Fujiwara M, Hachiya A, Koizumi H, Kuse N, Oka S, Duda A, Prendergast A, Crawford H, Leslie A, Brumme Z, Brumme C, Allen T, Brander C, Kaslow R, Tang J, Hunter E, Allen S, Mulenga J, Branch S, Roach T, John M, Mallal S, Ogwu A, Shapiro R, Prado JG, Fidler S, Weber J, Pybus OG, Klenerman P, Ndung'u T, Phillips R, Heckerman D, Harrigan PR, Walker BD, Takiguchi M, Goulder P. Kawashima Y, et al. Among authors: frater j. Nature. 2009 Apr 2;458(7238):641-5. doi: 10.1038/nature07746. Epub 2009 Feb 25. Nature. 2009. PMID: 19242411 Free PMC article.
Advancing the HIV cure agenda: the next 5 years.
Thornhill J, Fidler S, Frater J. Thornhill J, et al. Among authors: frater j. Curr Opin Infect Dis. 2015 Feb;28(1):1-9. doi: 10.1097/QCO.0000000000000123. Curr Opin Infect Dis. 2015. PMID: 25485650 Review.
Structured observations reveal slow HIV-1 CTL escape.
Roberts HE, Hurst J, Robinson N, Brown H, Flanagan P, Vass L, Fidler S, Weber J, Babiker A, Phillips RE, McLean AR, Frater J; SPARTAC trial investigators. Roberts HE, et al. Among authors: frater j. PLoS Genet. 2015 Feb 2;11(2):e1004914. doi: 10.1371/journal.pgen.1004914. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25642847 Free PMC article.
Immunological biomarkers predict HIV-1 viral rebound after treatment interruption.
Hurst J, Hoffmann M, Pace M, Williams JP, Thornhill J, Hamlyn E, Meyerowitz J, Willberg C, Koelsch KK, Robinson N, Brown H, Fisher M, Kinloch S, Cooper DA, Schechter M, Tambussi G, Fidler S, Babiker A, Weber J, Kelleher AD, Phillips RE, Frater J. Hurst J, et al. Among authors: frater j. Nat Commun. 2015 Oct 9;6:8495. doi: 10.1038/ncomms9495. Nat Commun. 2015. PMID: 26449164 Free PMC article. Clinical Trial.
Impact of pre-adapted HIV transmission.
Carlson JM, Du VY, Pfeifer N, Bansal A, Tan VY, Power K, Brumme CJ, Kreimer A, DeZiel CE, Fusi N, Schaefer M, Brockman MA, Gilmour J, Price MA, Kilembe W, Haubrich R, John M, Mallal S, Shapiro R, Frater J, Harrigan PR, Ndung'u T, Allen S, Heckerman D, Sidney J, Allen TM, Goulder PJ, Brumme ZL, Hunter E, Goepfert PA. Carlson JM, et al. Among authors: frater j. Nat Med. 2016 Jun;22(6):606-13. doi: 10.1038/nm.4100. Epub 2016 May 16. Nat Med. 2016. PMID: 27183217 Free PMC article.
273 results