Fraser JA - Search Results

1

Humulene Diepoxides from the Australian Arid Zone Herb Dysphania: Assignment of Aged Hops Constituents.

Tan YP, Agnew-Francis KA, Hofmann J, Savchenko AI, Lafontaine SR, Boyle GM, Bernhardt PV, Fraser JA, Shellhammer TH, Williams CM. Tan YP, et al. Among authors: fraser ja. Chemistry. 2020 Feb 3;26(7):1653-1660. doi: 10.1002/chem.201904420. Epub 2020 Jan 21. Chemistry. 2020. PMID: 31961021

2

Secondary metabolites of the sponge-derived fungus Acremonium persicinum.

Suciati, Fraser JA, Lambert LK, Pierens GK, Bernhardt PV, Garson MJ. Suciati, et al. Among authors: fraser ja. J Nat Prod. 2013 Aug 23;76(8):1432-40. doi: 10.1021/np4002114. Epub 2013 Jul 24. J Nat Prod. 2013. PMID: 23883432 Free article.

3

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase.

Lonhienne T, Nouwens A, Williams CM, Fraser JA, Lee YT, West NP, Guddat LW. Lonhienne T, et al. Among authors: fraser ja. Angew Chem Int Ed Engl. 2016 Mar 18;55(13):4247-51. doi: 10.1002/anie.201511985. Epub 2016 Feb 29. Angew Chem Int Ed Engl. 2016. PMID: 26924714

4

The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements.

Lonhienne T, Garcia MD, Fraser JA, Williams CM, Guddat LW. Lonhienne T, et al. Among authors: fraser ja. PLoS One. 2017 Feb 8;12(2):e0171443. doi: 10.1371/journal.pone.0171443. eCollection 2017. PLoS One. 2017. PMID: 28178302 Free PMC article.

5

Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.

Garcia MD, Chua SMH, Low YS, Lee YT, Agnew-Francis K, Wang JG, Nouwens A, Lonhienne T, Williams CM, Fraser JA, Guddat LW. Garcia MD, et al. Among authors: fraser ja. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9649-E9658. doi: 10.1073/pnas.1809422115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249642 Free PMC article.

6

Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian Dysphania Species That Suggests a Putative Biogenetic Link to Zerumbone.

Tan YP, Savchenko AI, Agnew-Francis KA, Boyle GM, Bernhardt PV, Fraser JA, Williams CM. Tan YP, et al. Among authors: fraser ja. J Nat Prod. 2020 May 22;83(5):1473-1479. doi: 10.1021/acs.jnatprod.9b01039. Epub 2020 Apr 17. J Nat Prod. 2020. PMID: 32302147

7

Structures of fungal and plant acetohydroxyacid synthases.

Lonhienne T, Low YS, Garcia MD, Croll T, Gao Y, Wang Q, Brillault L, Williams CM, Fraser JA, McGeary RP, West NP, Landsberg MJ, Rao Z, Schenk G, Guddat LW. Lonhienne T, et al. Among authors: fraser ja. Nature. 2020 Oct;586(7828):317-321. doi: 10.1038/s41586-020-2514-3. Epub 2020 Jul 8. Nature. 2020. PMID: 32640464

8

Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris.

Agnew-Francis KA, Tang Y, Lin X, Low YS, Wun SJ, Kuo A, Elias SMAS, Lonhienne T, Condon ND, Pimentel BNAS, Vergani CE, Smith MT, Fraser JA, Williams CM, Guddat LW. Agnew-Francis KA, et al. Among authors: fraser ja. ACS Infect Dis. 2020 Nov 13;6(11):2901-2912. doi: 10.1021/acsinfecdis.0c00229. Epub 2020 Oct 22. ACS Infect Dis. 2020. PMID: 32986949

9

Structure-activity relationships of bensulfuron methyl and its derivatives as novel agents against drug-resistant Candida auris.

Sun XW, Liu Y, Wang X, Li HR, Lin X, Tang JY, Xu Q, Agnew-Francis KA, Fraser JA, Sun ZJ, Guddat LW, Wang JG. Sun XW, et al. Among authors: fraser ja. Chem Biol Drug Des. 2024 Jan;103(1):e14364. doi: 10.1111/cbdd.14364. Epub 2023 Oct 8. Chem Biol Drug Des. 2024. PMID: 37806947

10

Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase.

Lee YT, Cui CJ, Chow EW, Pue N, Lonhienne T, Wang JG, Fraser JA, Guddat LW. Lee YT, et al. Among authors: fraser ja. J Med Chem. 2013 Jan 10;56(1):210-9. doi: 10.1021/jm301501k. Epub 2012 Dec 31. J Med Chem. 2013. PMID: 23237384

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