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Page 1
Safety profile of autologous macrophage therapy for liver cirrhosis.
Moroni F, Dwyer BJ, Graham C, Pass C, Bailey L, Ritchie L, Mitchell D, Glover A, Laurie A, Doig S, Hargreaves E, Fraser AR, Turner ML, Campbell JDM, McGowan NWA, Barry J, Moore JK, Hayes PC, Leeming DJ, Nielsen MJ, Musa K, Fallowfield JA, Forbes SJ. Moroni F, et al. Among authors: fraser ar. Nat Med. 2019 Oct;25(10):1560-1565. doi: 10.1038/s41591-019-0599-8. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591593 Clinical Trial.
Study protocol: a multicentre, open-label, parallel-group, phase 2, randomised controlled trial of autologous macrophage therapy for liver cirrhosis (MATCH).
Brennan PN, MacMillan M, Manship T, Moroni F, Glover A, Graham C, Semple S, Morris DM, Fraser AR, Pass C, McGowan NWA, Turner ML, Lachlan N, Dillon JF, Campbell JDM, Fallowfield JA, Forbes SJ. Brennan PN, et al. Among authors: fraser ar. BMJ Open. 2021 Nov 8;11(11):e053190. doi: 10.1136/bmjopen-2021-053190. BMJ Open. 2021. PMID: 34750149 Free PMC article.
Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis.
Fraser AR, Pass C, Burgoyne P, Atkinson A, Bailey L, Laurie A, W A McGowan N, Hamid A, Moore JK, Dwyer BJ, Turner ML, Forbes SJ, Campbell JDM. Fraser AR, et al. Cytotherapy. 2017 Sep;19(9):1113-1124. doi: 10.1016/j.jcyt.2017.05.009. Epub 2017 Jun 30. Cytotherapy. 2017. PMID: 28673774 Free PMC article.
Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.
Moore JK, Mackinnon AC, Wojtacha D, Pope C, Fraser AR, Burgoyne P, Bailey L, Pass C, Atkinson A, Mcgowan NW, Manson L, Turner ML, Campbell JD, Forbes SJ. Moore JK, et al. Among authors: fraser ar. Cytotherapy. 2015 Nov;17(11):1604-16. doi: 10.1016/j.jcyt.2015.07.016. Epub 2015 Sep 3. Cytotherapy. 2015. PMID: 26342993 Free PMC article.
Allogeneic Ex Vivo Expanded Corneal Epithelial Stem Cell Transplantation: A Randomized Controlled Clinical Trial.
Campbell JDM, Ahmad S, Agrawal A, Bienek C, Atkinson A, Mcgowan NWA, Kaye S, Mantry S, Ramaesh K, Glover A, Pelly J, MacRury C, MacDonald M, Hargreaves E, Barry J, Drain J, Cuthbertson B, Nerurkar L, Downing I, Fraser AR, Turner ML, Dhillon B. Campbell JDM, et al. Among authors: fraser ar. Stem Cells Transl Med. 2019 Apr;8(4):323-331. doi: 10.1002/sctm.18-0140. Epub 2019 Jan 28. Stem Cells Transl Med. 2019. PMID: 30688407 Free PMC article. Clinical Trial.
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease.
Hallett JM, Ferreira-Gonzalez S, Man TY, Kilpatrick AM, Esser H, Thirlwell K, Macmillan MT, Rodrigo-Torres D, Dwyer BJ, Gadd VL, Ashmore-Harris C, Lu WY, Thomson JP, Jansen MA, O'Duibhir E, Starkey Lewis PJ, Campana L, Aird RE, Bate TSR, Fraser AR, Campbell JDM, Oniscu GC, Hay DC, Callanan A, Forbes SJ. Hallett JM, et al. Among authors: fraser ar. Cell Stem Cell. 2022 Mar 3;29(3):355-371.e10. doi: 10.1016/j.stem.2022.02.006. Cell Stem Cell. 2022. PMID: 35245467 Free PMC article.
Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization.
Forbes S, Bond AR, Thirlwell KL, Burgoyne P, Samuel K, Noble J, Borthwick G, Colligan D, McGowan NWA, Lewis PS, Fraser AR, Mountford JC, Carter RN, Morton NM, Turner ML, Graham GJ, Campbell JDM. Forbes S, et al. Among authors: fraser ar. Sci Transl Med. 2020 Jan 15;12(526):eaan5907. doi: 10.1126/scitranslmed.aan5907. Sci Transl Med. 2020. PMID: 31941825
65 results