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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.
Demontis D, Walters GB, Athanasiadis G, Walters R, Therrien K, Nielsen TT, Farajzadeh L, Voloudakis G, Bendl J, Zeng B, Zhang W, Grove J, Als TD, Duan J, Satterstrom FK, Bybjerg-Grauholm J, Bækved-Hansen M, Gudmundsson OO, Magnusson SH, Baldursson G, Davidsdottir K, Haraldsdottir GS, Agerbo E, Hoffman GE, Dalsgaard S, Martin J, Ribasés M, Boomsma DI, Soler Artigas M, Roth Mota N, Howrigan D, Medland SE, Zayats T, Rajagopal VM; ADHD Working Group of the Psychiatric Genomics Consortium; iPSYCH-Broad Consortium; Nordentoft M, Mors O, Hougaard DM, Mortensen PB, Daly MJ, Faraone SV, Stefansson H, Roussos P, Franke B, Werge T, Neale BM, Stefansson K, Børglum AD. Demontis D, et al. Among authors: franke b. Nat Genet. 2023 Feb;55(2):198-208. doi: 10.1038/s41588-022-01285-8. Epub 2023 Jan 26. Nat Genet. 2023. PMID: 36702997 Free PMC article.
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes.
Brookes K, Xu X, Chen W, Zhou K, Neale B, Lowe N, Anney R, Franke B, Gill M, Ebstein R, Buitelaar J, Sham P, Campbell D, Knight J, Andreou P, Altink M, Arnold R, Boer F, Buschgens C, Butler L, Christiansen H, Feldman L, Fleischman K, Fliers E, Howe-Forbes R, Goldfarb A, Heise A, Gabriëls I, Korn-Lubetzki I, Johansson L, Marco R, Medad S, Minderaa R, Mulas F, Müller U, Mulligan A, Rabin K, Rommelse N, Sethna V, Sorohan J, Uebel H, Psychogiou L, Weeks A, Barrett R, Craig I, Banaschewski T, Sonuga-Barke E, Eisenberg J, Kuntsi J, Manor I, McGuffin P, Miranda A, Oades RD, Plomin R, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Thompson M, Faraone SV, Asherson P. Brookes K, et al. Among authors: franke b. Mol Psychiatry. 2006 Oct;11(10):934-53. doi: 10.1038/sj.mp.4001869. Epub 2006 Aug 8. Mol Psychiatry. 2006. PMID: 16894395 Free article.
Confirmation that a specific haplotype of the dopamine transporter gene is associated with combined-type ADHD.
Asherson P, Brookes K, Franke B, Chen W, Gill M, Ebstein RP, Buitelaar J, Banaschewski T, Sonuga-Barke E, Eisenberg J, Manor I, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Faraone SV. Asherson P, et al. Among authors: franke b. Am J Psychiatry. 2007 Apr;164(4):674-7. doi: 10.1176/ajp.2007.164.4.674. Am J Psychiatry. 2007. PMID: 17403983 Free article.
Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth.
Brookes KJ, Neale B, Xu X, Thapar A, Gill M, Langley K, Hawi Z, Mill J, Taylor E, Franke B, Chen W, Ebstein R, Buitelaar J, Banaschewski T, Sonuga-Barke E, Eisenberg J, Manor I, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Faraone SV, Asherson P. Brookes KJ, et al. Among authors: franke b. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5;147B(1):94-9. doi: 10.1002/ajmg.b.30562. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 17525975
Partial replication of a DRD4 association in ADHD individuals using a statistically derived quantitative trait for ADHD in a family-based association test.
Lasky-Su J, Banaschewski T, Buitelaar J, Franke B, Brookes K, Sonuga-Barke E, Ebstein R, Eisenberg J, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Zhou K, Thompson M, Asherson P, Faraone SV. Lasky-Su J, et al. Among authors: franke b. Biol Psychiatry. 2007 Nov 1;62(9):985-90. doi: 10.1016/j.biopsych.2007.03.006. Epub 2007 Jun 8. Biol Psychiatry. 2007. PMID: 17560555
Population differences in the International Multi-Centre ADHD Gene Project.
Neale BM, Sham PC, Purcell S, Banaschewski T, Buitelaar J, Franke B, Sonuga-Barke E, Ebstein R, Eisenberg J, Mulligan A, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Thompson M, Chen W, Zhou K, Asherson P, Faraone SV. Neale BM, et al. Among authors: franke b. Genet Epidemiol. 2008 Feb;32(2):98-107. doi: 10.1002/gepi.20265. Genet Epidemiol. 2008. PMID: 17868146 Free article.
Parent of origin effects in attention/deficit hyperactivity disorder (ADHD): analysis of data from the international multicenter ADHD genetics (IMAGE) program.
Anney RJ, Hawi Z, Sheehan K, Mulligan A, Pinto C, Brookes KJ, Xu X, Zhou K, Franke B, Buitelaar J, Vermeulen SH, Banaschewski T, Sonuga-Barke E, Ebstein R, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rommelse N, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Thompson M, Asherson P, Faraone SV, Gill M. Anney RJ, et al. Among authors: franke b. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1495-500. doi: 10.1002/ajmg.b.30659. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 18163388
DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage.
Chen W, Zhou K, Sham P, Franke B, Kuntsi J, Campbell D, Fleischman K, Knight J, Andreou P, Arnold R, Altink M, Boer F, Boholst MJ, Buschgens C, Butler L, Christiansen H, Fliers E, Howe-Forbes R, Gabriëls I, Heise A, Korn-Lubetzki I, Marco R, Medad S, Minderaa R, Müller UC, Mulligan A, Psychogiou L, Rommelse N, Sethna V, Uebel H, McGuffin P, Plomin R, Banaschewski T, Buitelaar J, Ebstein R, Eisenberg J, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Thompson M, Faraone SV, Asherson P. Chen W, et al. Among authors: franke b. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1450-60. doi: 10.1002/ajmg.b.30672. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 18189238
Co-transmission of conduct problems with attention-deficit/hyperactivity disorder: familial evidence for a distinct disorder.
Christiansen H, Chen W, Oades RD, Asherson P, Taylor EA, Lasky-Su J, Zhou K, Banaschewski T, Buschgens C, Franke B, Gabriels I, Manor I, Marco R, Müller UC, Mulligan A, Psychogiou L, Rommelse NN, Uebel H, Buitelaar J, Ebstein RP, Eisenberg J, Gill M, Miranda A, Mulas F, Roeyers H, Rothenberger A, Sergeant JA, Sonuga-Barke EJ, Steinhausen HC, Thompson M, Faraone SV. Christiansen H, et al. Among authors: franke b. J Neural Transm (Vienna). 2008;115(2):163-75. doi: 10.1007/s00702-007-0837-y. Epub 2008 Jan 16. J Neural Transm (Vienna). 2008. PMID: 18200434 Free article.
663 results