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Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects.
Fragale A, Stellacci E, Romagnoli G, Licursi V, Parlato S, Canini I, Remedi G, Buoncervello M, Matarrese P, Pedace L, Ascione B, Pizzi S, Tartaglia M, D'Atri S, Presutti C, Capone I, Gabriele L. Fragale A, et al. Int J Cancer. 2023 Sep 1;153(5):1080-1095. doi: 10.1002/ijc.34602. Epub 2023 Jun 9. Int J Cancer. 2023. PMID: 37293858
Impaired myelopoiesis in mice devoid of interferon regulatory factor 1.
Testa U, Stellacci E, Pelosi E, Sestili P, Venditti M, Orsatti R, Fragale A, Petrucci E, Pasquini L, Belardelli F, Gabriele L, Battistini A. Testa U, et al. Among authors: fragale a. Leukemia. 2004 Nov;18(11):1864-71. doi: 10.1038/sj.leu.2403472. Leukemia. 2004. PMID: 15385939
Critical role of IRF-8 in negative regulation of TLR3 expression by Src homology 2 domain-containing protein tyrosine phosphatase-2 activity in human myeloid dendritic cells.
Fragale A, Stellacci E, Ilari R, Remoli AL, Lanciotti A, Perrotti E, Shytaj I, Orsatti R, Lawrence HR, Lawrence NJ, Wu J, Rehli M, Ozato K, Battistini A. Fragale A, et al. J Immunol. 2011 Feb 15;186(4):1951-62. doi: 10.4049/jimmunol.1000918. Epub 2011 Jan 10. J Immunol. 2011. PMID: 21220691 Free PMC article.
A multidisciplinary study using in vivo tumor models and microfluidic cell-on-chip approach to explore the cross-talk between cancer and immune cells.
Mattei F, Schiavoni G, De Ninno A, Lucarini V, Sestili P, Sistigu A, Fragale A, Sanchez M, Spada M, Gerardino A, Belardelli F, Businaro L, Gabriele L. Mattei F, et al. Among authors: fragale a. J Immunotoxicol. 2014 Oct;11(4):337-46. doi: 10.3109/1547691X.2014.891677. Epub 2014 Mar 6. J Immunotoxicol. 2014. PMID: 24597645
IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer.
Buoncervello M, Romagnoli G, Buccarelli M, Fragale A, Toschi E, Parlato S, Lucchetti D, Macchia D, Spada M, Canini I, Sanchez M, Falchi M, Musella M, Biffoni M, Belardelli F, Capone I, Sgambato A, Vitiani LR, Gabriele L. Buoncervello M, et al. Among authors: fragale a. Oncotarget. 2016 May 3;7(18):26361-73. doi: 10.18632/oncotarget.8379. Oncotarget. 2016. PMID: 27028869 Free PMC article.
3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells.
Parlato S, De Ninno A, Molfetta R, Toschi E, Salerno D, Mencattini A, Romagnoli G, Fragale A, Roccazzello L, Buoncervello M, Canini I, Bentivegna E, Falchi M, Bertani FR, Gerardino A, Martinelli E, Natale C, Paolini R, Businaro L, Gabriele L. Parlato S, et al. Among authors: fragale a. Sci Rep. 2017 Apr 24;7(1):1093. doi: 10.1038/s41598-017-01013-x. Sci Rep. 2017. PMID: 28439087 Free PMC article.
41 results