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Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis.
Frénois F, Baulard AR, Villeret V. Frénois F, et al. Tuberculosis (Edinb). 2006 Mar;86(2):110-4. doi: 10.1016/j.tube.2005.07.005. Epub 2005 Oct 21. Tuberculosis (Edinb). 2006. PMID: 16243584 Review.
Two EthR crystal structures have been reported recently, either in a ligand-bound (Frenois F, Engohang-Ndong J, Locht C, Baulard AR, Villeret V. Mol Cell 2004; 16: 301-7) or in a presumed apo conformation (Dover LG, Corsino PE, Daniels IR, Cocklin SL, Tatituri V, Be …
Two EthR crystal structures have been reported recently, either in a ligand-bound (Frenois F, Engohang-Ndong J, Locht C, Baula …
Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Willand N, Dirié B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Déprez-Poulain R, Delcroix G, Frénois F, Aumercier M, Locht C, Villeret V, Déprez B, Baulard AR. Willand N, et al. Among authors: frenois f. Nat Med. 2009 May;15(5):537-44. doi: 10.1038/nm.1950. Epub 2009 May 3. Nat Med. 2009. PMID: 19412174
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Carette X, Blondiaux N, Willery E, Hoos S, Lecat-Guillet N, Lens Z, Wohlkönig A, Wintjens R, Soror SH, Frénois F, Dirié B, Villeret V, England P, Lippens G, Deprez B, Locht C, Willand N, Baulard AR. Carette X, et al. Among authors: frenois f. Nucleic Acids Res. 2012 Apr;40(7):3018-30. doi: 10.1093/nar/gkr1113. Epub 2011 Dec 9. Nucleic Acids Res. 2012. PMID: 22156370 Free PMC article.
Membrane-bound mucin modular domains: from structure to function.
Jonckheere N, Skrypek N, Frénois F, Van Seuningen I. Jonckheere N, et al. Among authors: frenois f. Biochimie. 2013 Jun;95(6):1077-86. doi: 10.1016/j.biochi.2012.11.005. Epub 2012 Nov 20. Biochimie. 2013. PMID: 23178705 Free article. Review.
The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways.
Jonckheere N, Skrypek N, Merlin J, Dessein AF, Dumont P, Leteurtre E, Harris A, Desseyn JL, Susini C, Frénois F, Van Seuningen I. Jonckheere N, et al. Among authors: frenois f. PLoS One. 2012;7(2):e32232. doi: 10.1371/journal.pone.0032232. Epub 2012 Feb 29. PLoS One. 2012. PMID: 22393391 Free PMC article.
43 results