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Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems.
Chen X, Ravindra Kumar S, Adams CD, Yang D, Wang T, Wolfe DA, Arokiaraj CM, Ngo V, Campos LJ, Griffiths JA, Ichiki T, Mazmanian SK, Osborne PB, Keast JR, Miller CT, Fox AS, Chiu IM, Gradinaru V. Chen X, et al. Among authors: fox as. Neuron. 2022 Jul 20;110(14):2242-2257.e6. doi: 10.1016/j.neuron.2022.05.003. Epub 2022 May 27. Neuron. 2022. PMID: 35643078 Free PMC article.
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore BB, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V. Chen X, et al. Among authors: fox as. Nat Commun. 2023 Jun 8;14(1):3345. doi: 10.1038/s41467-023-38582-7. Nat Commun. 2023. PMID: 37291094 Free PMC article.
Overexpressing Corticotropin-Releasing Factor in the Primate Amygdala Increases Anxious Temperament and Alters Its Neural Circuit.
Kalin NH, Fox AS, Kovner R, Riedel MK, Fekete EM, Roseboom PH, Tromp do PM, Grabow BP, Olsen ME, Brodsky EK, McFarlin DR, Alexander AL, Emborg ME, Block WF, Fudge JL, Oler JA. Kalin NH, et al. Among authors: fox as. Biol Psychiatry. 2016 Sep 1;80(5):345-55. doi: 10.1016/j.biopsych.2016.01.010. Epub 2016 Jan 30. Biol Psychiatry. 2016. PMID: 27016385 Free PMC article.
Dorsal Amygdala Neurotrophin-3 Decreases Anxious Temperament in Primates.
Fox AS, Souaiaia T, Oler JA, Kovner R, Kim JMH, Nguyen J, French DA, Riedel MK, Fekete EM, Rabska MR, Olsen ME, Brodsky EK, Alexander AL, Block WF, Roseboom PH, Knowles JA, Kalin NH. Fox AS, et al. Biol Psychiatry. 2019 Dec 15;86(12):881-889. doi: 10.1016/j.biopsych.2019.06.022. Epub 2019 Jul 2. Biol Psychiatry. 2019. PMID: 31422797 Free PMC article.
Transcriptional Profiling of Primate Central Nucleus of the Amygdala Neurons to Understand the Molecular Underpinnings of Early-Life Anxious Temperament.
Kovner R, Souaiaia T, Fox AS, French DA, Goss CE, Roseboom PH, Oler JA, Riedel MK, Fekete EM, Fudge JL, Knowles JA, Kalin NH. Kovner R, et al. Among authors: fox as. Biol Psychiatry. 2020 Oct 15;88(8):638-648. doi: 10.1016/j.biopsych.2020.05.009. Epub 2020 May 19. Biol Psychiatry. 2020. PMID: 32709417 Free PMC article.
196 results