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Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice.
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM. Gregorius J, et al. Among authors: magraoui fe. Basic Res Cardiol. 2021 Jun 8;116(1):40. doi: 10.1007/s00395-021-00881-9. Basic Res Cardiol. 2021. PMID: 34105014 Free PMC article.
Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales.
Ludwig AK, De Miroschedji K, Doeppner TR, Börger V, Ruesing J, Rebmann V, Durst S, Jansen S, Bremer M, Behrmann E, Singer BB, Jastrow H, Kuhlmann JD, El Magraoui F, Meyer HE, Hermann DM, Opalka B, Raunser S, Epple M, Horn PA, Giebel B. Ludwig AK, et al. Among authors: el magraoui f. J Extracell Vesicles. 2018 Oct 17;7(1):1528109. doi: 10.1080/20013078.2018.1528109. eCollection 2018. J Extracell Vesicles. 2018. PMID: 30357008 Free PMC article.
LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease.
Schrötter A, Oberhaus A, Kolbe K, Seger S, Mastalski T, El Magraoui F, Hoffmann-Posorske E, Bohnert M, Deckert J, Braun C, Graw M, Schmitz C, Arzberger T, Loosse C, Heinsen H, Meyer HE, Müller T. Schrötter A, et al. Among authors: el magraoui f. Biochim Biophys Acta Proteins Proteom. 2017 Jun;1865(6):703-714. doi: 10.1016/j.bbapap.2017.03.013. Epub 2017 Apr 2. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28377147
Key players in neurodegenerative disorders in focus-New insights into the proteomic profile of Alzheimer's disease, schizophrenia, ALS, and multiple sclerosis-24th HUPO BPP Workshop: September 29, 2015, Vancouver, Canada.
Schrötter A, Park YM, Marcus K, Martins-de-Souza D, Nilsson P, Magraoui FE, Meyer HE, Grinberg LT. Schrötter A, et al. Among authors: magraoui fe. Proteomics. 2016 Apr;16(7):1047-50. doi: 10.1002/pmic.201600047. Proteomics. 2016. PMID: 26872682
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