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Page 1
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension.
Desai AS, Webb DJ, Taubel J, Casey S, Cheng Y, Robbie GJ, Foster D, Huang SA, Rhyee S, Sweetser MT, Bakris GL. Desai AS, et al. Among authors: foster d. N Engl J Med. 2023 Jul 20;389(3):228-238. doi: 10.1056/NEJMoa2208391. N Engl J Med. 2023. PMID: 37467498 Clinical Trial.
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease.
Bovée DM, Ren L, Uijl E, Clahsen-van Groningen MC, van Veghel R, Garrelds IM, Domenig O, Poglitsch M, Zlatev I, Kim JB, Huang S, Melton L, Lu X, Hoorn EJ, Foster D, Danser AHJ. Bovée DM, et al. Among authors: foster d. Hypertension. 2021 May 5;77(5):1600-1612. doi: 10.1161/HYPERTENSIONAHA.120.16876. Epub 2021 Mar 15. Hypertension. 2021. PMID: 33719507
Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.
Cruz-López EO, Ren L, Uijl E, Clahsen-van Groningen MC, van Veghel R, Garrelds IM, Domenig O, Poglitsch M, Zlatev I, Rooney T, Kasper A, Nioi P, Foster D, Danser AHJ. Cruz-López EO, et al. Among authors: foster d. Br J Pharmacol. 2023 Jan;180(1):80-93. doi: 10.1111/bph.15955. Epub 2022 Oct 2. Br J Pharmacol. 2023. PMID: 36106615 Free PMC article.
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Sehgal A, Barros S, Ivanciu L, Cooley B, Qin J, Racie T, Hettinger J, Carioto M, Jiang Y, Brodsky J, Prabhala H, Zhang X, Attarwala H, Hutabarat R, Foster D, Milstein S, Charisse K, Kuchimanchi S, Maier MA, Nechev L, Kandasamy P, Kel'in AV, Nair JK, Rajeev KG, Manoharan M, Meyers R, Sorensen B, Simon AR, Dargaud Y, Negrier C, Camire RM, Akinc A. Sehgal A, et al. Among authors: foster d. Nat Med. 2015 May;21(5):492-7. doi: 10.1038/nm.3847. Epub 2015 Apr 13. Nat Med. 2015. PMID: 25849132
Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen.
Uijl E, Ye D, Ren L, Mirabito Colafella KM, van Veghel R, Garrelds IM, Lu HS, Daugherty A, Hoorn EJ, Nioi P, Foster D, Danser AHJ. Uijl E, et al. Among authors: foster d. J Am Heart Assoc. 2022 Aug 2;11(15):e026426. doi: 10.1161/JAHA.122.026426. Epub 2022 Jul 25. J Am Heart Assoc. 2022. PMID: 35876413 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36027119
Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo.
Foster DJ, Barros S, Duncan R, Shaikh S, Cantley W, Dell A, Bulgakova E, O'Shea J, Taneja N, Kuchimanchi S, Sherrill CB, Akinc A, Hinkle G, Seila White AC, Pang B, Charisse K, Meyers R, Manoharan M, Elbashir SM. Foster DJ, et al. RNA. 2012 Mar;18(3):557-68. doi: 10.1261/rna.031120.111. Epub 2012 Jan 31. RNA. 2012. PMID: 22294662 Free PMC article.
Preclinical Development of a Subcutaneous ALAS1 RNAi Therapeutic for Treatment of Hepatic Porphyrias Using Circulating RNA Quantification.
Chan A, Liebow A, Yasuda M, Gan L, Racie T, Maier M, Kuchimanchi S, Foster D, Milstein S, Charisse K, Sehgal A, Manoharan M, Meyers R, Fitzgerald K, Simon A, Desnick RJ, Querbes W. Chan A, et al. Among authors: foster d. Mol Ther Nucleic Acids. 2015 Nov 3;4(11):e263. doi: 10.1038/mtna.2015.36. Mol Ther Nucleic Acids. 2015. PMID: 26528940 Free PMC article.
2,238 results