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Page 1
The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening.
Hartman G, Humphries P, Hughes R, Ho A, Montgomery R, Deshpande A, Mahanta M, Tronnes S, Cowdin S, He X, Liu F, Zhang L, Liu C, Dou D, Li J, Spasic A, Coll R, Marleaux M, Hochheiser IV, Geyer M, Rubin P, Fortney K, Wilhelmsen K. Hartman G, et al. Among authors: fortney k. Bioorg Med Chem Lett. 2024 Apr 1;102:129675. doi: 10.1016/j.bmcl.2024.129675. Epub 2024 Feb 28. Bioorg Med Chem Lett. 2024. PMID: 38417632
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19.
Wong LR, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Pezzulo AA, Szachowicz PJ, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Meyerholz DK, Fortney K, McCray PB Jr, Perlman S. Wong LR, et al. Among authors: fortney k. bioRxiv [Preprint]. 2021 Apr 21:2021.04.20.440676. doi: 10.1101/2021.04.20.440676. bioRxiv. 2021. PMID: 33907749 Free PMC article. Preprint.
Validation of biomarkers of aging.
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. Moqri M, et al. Among authors: fortney k. Nat Med. 2024 Feb;30(2):360-372. doi: 10.1038/s41591-023-02784-9. Epub 2024 Feb 14. Nat Med. 2024. PMID: 38355974 Free PMC article. Review.
Defining a longevity biotechnology company.
Boekstein N, Barzilai N, Bertram A, Betts-LaCroix J, Fortney K, Helliwell SB, Hufford M, Mannick J, McLaughlin J, Mellon J, Morgen E, Regge N, Robinton DA, Sinclair DA, Young S, Starr R, Zhavoronkov A, Peyer J. Boekstein N, et al. Among authors: fortney k. Nat Biotechnol. 2023 Aug;41(8):1053-1055. doi: 10.1038/s41587-023-01854-0. Nat Biotechnol. 2023. PMID: 37365260 No abstract available.
Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype.
Donlon TA, Morris BJ, Chen R, Lim E, Morgen EK, Fortney K, Shah N, Masaki KH, Willcox BJ. Donlon TA, et al. Among authors: fortney k. Geroscience. 2023 Aug;45(4):2303-2324. doi: 10.1007/s11357-023-00740-6. Epub 2023 Mar 7. Geroscience. 2023. PMID: 36881352 Free PMC article.
Erratum for Brothwell et al., "Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-Inflammatory Environment in the Human Host".
Brothwell JA, Fortney KR, Gao H, Wilson LS, Andrews CF, Tran TM, Hu X, Batteiger TA, Barnes S, Liu Y, Spinola SM. Brothwell JA, et al. Among authors: fortney kr. mBio. 2023 Feb 28;14(1):e0352222. doi: 10.1128/mbio.03522-22. Epub 2023 Feb 6. mBio. 2023. PMID: 36744942 Free PMC article. No abstract available.
Two Streptococcus pyogenes emm types and several anaerobic bacterial species are associated with idiopathic cutaneous ulcers in children after community-based mass treatment with azithromycin.
Griesenauer B, Xing Y, Fortney KR, Gao X, González-Beiras C, Nelson DE, Ren J, Mitjà O, Dong Q, Spinola SM. Griesenauer B, et al. Among authors: fortney kr. PLoS Negl Trop Dis. 2022 Dec 19;16(12):e0011009. doi: 10.1371/journal.pntd.0011009. eCollection 2022 Dec. PLoS Negl Trop Dis. 2022. PMID: 36534698 Free PMC article.
94 results