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Page 1
Putative adverse outcome pathways relevant to neurotoxicity.
Bal-Price A, Crofton KM, Sachana M, Shafer TJ, Behl M, Forsby A, Hargreaves A, Landesmann B, Lein PJ, Louisse J, Monnet-Tschudi F, Paini A, Rolaki A, Schrattenholz A, Suñol C, van Thriel C, Whelan M, Fritsche E. Bal-Price A, et al. Among authors: forsby a. Crit Rev Toxicol. 2015 Jan;45(1):83-91. doi: 10.3109/10408444.2014.981331. Crit Rev Toxicol. 2015. PMID: 25605028 Free PMC article. Review.
Adverse outcome pathways: opportunities, limitations and open questions.
Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG. Leist M, et al. Among authors: forsby a. Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19. Arch Toxicol. 2017. PMID: 29051992 Review.
Gene-environment interactions: neurodegeneration in non-mammals and mammals.
Aschner M, Levin ED, Suñol C, Olopade JO, Helmcke KJ, Avila DS, Sledge D, Ali RH, Upchurch L, Donerly S, Linney E, Forsby A, Ponnuru P, Connor JR. Aschner M, et al. Among authors: forsby a. Neurotoxicology. 2010 Sep;31(5):582-8. doi: 10.1016/j.neuro.2010.03.008. Epub 2010 Mar 30. Neurotoxicology. 2010. PMID: 20359493 Free PMC article. Review.
Development of a neurotoxicity assay that is tuned to detect mitochondrial toxicants.
Delp J, Funke M, Rudolf F, Cediel A, Bennekou SH, van der Stel W, Carta G, Jennings P, Toma C, Gardner I, van de Water B, Forsby A, Leist M. Delp J, et al. Among authors: forsby a. Arch Toxicol. 2019 Jun;93(6):1585-1608. doi: 10.1007/s00204-019-02473-y. Epub 2019 Jun 12. Arch Toxicol. 2019. PMID: 31190196
Neuronal in vitro models for the estimation of acute systemic toxicity.
Forsby A, Bal-Price AK, Camins A, Coecke S, Fabre N, Gustafsson H, Honegger P, Kinsner-Ovaskainen A, Pallas M, Rimbau V, Rodríguez-Farré E, Suñol C, Vericat JA, Zurich MG. Forsby A, et al. Toxicol In Vitro. 2009 Dec;23(8):1564-9. doi: 10.1016/j.tiv.2009.07.017. Epub 2009 Jul 15. Toxicol In Vitro. 2009. PMID: 19615435
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Among authors: forsby a. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors.
Delp J, Cediel-Ulloa A, Suciu I, Kranaster P, van Vugt-Lussenburg BM, Munic Kos V, van der Stel W, Carta G, Bennekou SH, Jennings P, van de Water B, Forsby A, Leist M. Delp J, et al. Among authors: forsby a. Arch Toxicol. 2021 Feb;95(2):591-615. doi: 10.1007/s00204-020-02970-5. Epub 2021 Jan 29. Arch Toxicol. 2021. PMID: 33512557 Free PMC article.
New approach methods (NAMs) supporting read-across: Two neurotoxicity AOP-based IATA case studies.
Van der Stel W, Carta G, Eakins J, Delp J, Suciu I, Forsby A, Cediel-Ulloa A, Attoff K, Troger F, Kamp H, Gardner I, Zdrazil B, Moné MJ, Ecker GF, Pastor M, Gómez-Tamayo JC, White A, Danen EHJ, Leist M, Walker P, Jennings P, Hougaard Bennekou S, Van de Water B. Van der Stel W, et al. Among authors: forsby a. ALTEX. 2021;38(4):615-635. doi: 10.14573/altex.2103051. Epub 2021 Jun 10. ALTEX. 2021. PMID: 34114044 Free article.
64 results