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Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin.
Berthelet J, Foroutan M, Bhuva DD, Whitfield HJ, El-Saafin F, Cursons J, Serrano A, Merdas M, Lim E, Charafe-Jauffret E, Ginestier C, Ernst M, Hollande F, Anderson RL, Pal B, Yeo B, Davis MJ, Merino D. Berthelet J, et al. Among authors: foroutan m. Cancers (Basel). 2022 May 13;14(10):2404. doi: 10.3390/cancers14102404. Cancers (Basel). 2022. PMID: 35626009 Free PMC article.
Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines.
Cursons J, Leuchowius KJ, Waltham M, Tomaskovic-Crook E, Foroutan M, Bracken CP, Redfern A, Crampin EJ, Street I, Davis MJ, Thompson EW. Cursons J, et al. Among authors: foroutan m. Cell Commun Signal. 2015 May 15;13:26. doi: 10.1186/s12964-015-0106-x. Cell Commun Signal. 2015. PMID: 25975820 Free PMC article.
Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT.
Cursons J, Pillman KA, Scheer KG, Gregory PA, Foroutan M, Hediyeh-Zadeh S, Toubia J, Crampin EJ, Goodall GJ, Bracken CP, Davis MJ. Cursons J, et al. Among authors: foroutan m. Cell Syst. 2018 Jul 25;7(1):77-91.e7. doi: 10.1016/j.cels.2018.05.019. Epub 2018 Jul 11. Cell Syst. 2018. PMID: 30007539 Free article.
Single sample scoring of molecular phenotypes.
Foroutan M, Bhuva DD, Lyu R, Horan K, Cursons J, Davis MJ. Foroutan M, et al. BMC Bioinformatics. 2018 Nov 6;19(1):404. doi: 10.1186/s12859-018-2435-4. BMC Bioinformatics. 2018. PMID: 30400809 Free PMC article.
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation.
Chüeh AC, Advani G, Foroutan M, Smith J, Ng N, Nandurkar H, Lio DS, Zhu HJ, Chong YP, Verkade H, Fujita DJ, Bjorge J, Basheer F, Lim JP, Luk I, Dhillon A, Sakthianandeswaren A, Mouradov D, Sieber O, Hollande F, Mariadason JM, Cheng HC. Chüeh AC, et al. Among authors: foroutan m. Oncogene. 2021 Apr;40(17):3015-3029. doi: 10.1038/s41388-021-01755-z. Epub 2021 Mar 25. Oncogene. 2021. PMID: 33767439
TGFβ and CIS Inhibition Overcomes NK-cell Suppression to Restore Antitumor Immunity.
Souza-Fonseca-Guimaraes F, Rossi GR, Dagley LF, Foroutan M, McCulloch TR, Yousef J, Park HY, Gunter JH, Beavis PA, Lin CY, Hediyeh-Zadeh S, Camilleri T, Davis MJ, Huntington ND. Souza-Fonseca-Guimaraes F, et al. Among authors: foroutan m. Cancer Immunol Res. 2022 Sep 1;10(9):1047-1054. doi: 10.1158/2326-6066.CIR-21-1052. Cancer Immunol Res. 2022. PMID: 35759796
175 results