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The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase.
Vasconez AE, Janetzko P, Oo JA, Pflüger-Müller B, Ratiu C, Gu L, Helin K, Geisslinger G, Fleming I, Schröder K, Fork C, Brandes RP, Leisegang MS. Vasconez AE, et al. Among authors: fork c. Acta Physiol (Oxf). 2019 Jan;225(1):e13168. doi: 10.1111/apha.13168. Epub 2018 Aug 25. Acta Physiol (Oxf). 2019. PMID: 30076673
Epigenetic Regulation of Angiogenesis by JARID1B-Induced Repression of HOXA5.
Fork C, Gu L, Hitzel J, Josipovic I, Hu J, SzeKa Wong M, Ponomareva Y, Albert M, Schmitz SU, Uchida S, Fleming I, Helin K, Steinhilber D, Leisegang MS, Brandes RP. Fork C, et al. Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1645-52. doi: 10.1161/ATVBAHA.115.305561. Epub 2015 May 28. Arterioscler Thromb Vasc Biol. 2015. PMID: 26023081
PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells.
Josipovic I, Fork C, Preussner J, Prior KK, Iloska D, Vasconez AE, Labocha S, Angioni C, Thomas D, Ferreirós N, Looso M, Pullamsetti SS, Geisslinger G, Steinhilber D, Brandes RP, Leisegang MS. Josipovic I, et al. Among authors: fork c. Acta Physiol (Oxf). 2016 Sep;218(1):13-27. doi: 10.1111/apha.12700. Epub 2016 May 20. Acta Physiol (Oxf). 2016. PMID: 27124368
The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration.
Gu L, Hitzel J, Moll F, Kruse C, Malik RA, Preussner J, Looso M, Leisegang MS, Steinhilber D, Brandes RP, Fork C. Gu L, et al. Among authors: fork c. PLoS One. 2016 Jan 11;11(1):e0146645. doi: 10.1371/journal.pone.0146645. eCollection 2016. PLoS One. 2016. PMID: 26751588 Free PMC article.
Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.
Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP. Leisegang MS, et al. Among authors: fork c. Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28. Circulation. 2017. PMID: 28351900 Free PMC article.
Long noncoding RNA LISPR1 is required for S1P signaling and endothelial cell function.
Josipovic I, Pflüger B, Fork C, Vasconez AE, Oo JA, Hitzel J, Seredinski S, Gamen E, Heringdorf DMZ, Chen W, Looso M, Pullamsetti SS, Brandes RP, Leisegang MS. Josipovic I, et al. Among authors: fork c. J Mol Cell Cardiol. 2018 Mar;116:57-68. doi: 10.1016/j.yjmcc.2018.01.015. Epub 2018 Feb 3. J Mol Cell Cardiol. 2018. PMID: 29408197
The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells.
Pflüger-Müller B, Oo JA, Heering J, Warwick T, Proschak E, Günther S, Looso M, Rezende F, Fork C, Geisslinger G, Thomas D, Gurke R, Steinhilber D, Schulz M, Leisegang MS, Brandes RP. Pflüger-Müller B, et al. Among authors: fork c. Basic Res Cardiol. 2020 Apr 22;115(3):34. doi: 10.1007/s00395-020-0793-3. Basic Res Cardiol. 2020. PMID: 32323032 Free PMC article.
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.
Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, Thomas D, Giral H, Schreiber Y, Geisslinger G, Fork C, Yang X, Sigala F, Romanoski CE, Kroll J, Jo H, Landmesser U, Lusis AJ, Namgaladze D, Fleming I, Leisegang MS, Zhu J, Brandes RP. Hitzel J, et al. Among authors: fork c. Nat Commun. 2018 Jun 12;9(1):2292. doi: 10.1038/s41467-018-04602-0. Nat Commun. 2018. PMID: 29895827 Free PMC article.
23 results