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Prime and pull of T cell responses against cancer-exogenous antigens is effective against CPI-resistant tumors.
Troise F, Leoni G, Sasso E, Del Sorbo M, Esposito M, Romano G, Allocca S, Froechlich G, Cotugno G, Capone S, Folgori A, Scarselli E, D'Alise AM, Nicosia A. Troise F, et al. Among authors: folgori a. Mol Ther Oncol. 2024 Jan 10;32(1):200760. doi: 10.1016/j.omton.2024.200760. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596303 Free PMC article.
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates.
Capone S, Naddeo M, D'Alise AM, Abbate A, Grazioli F, Del Gaudio A, Del Sorbo M, Esposito ML, Ammendola V, Perretta G, Taglioni A, Colloca S, Nicosia A, Cortese R, Folgori A. Capone S, et al. Among authors: folgori a. Mol Ther. 2014 May;22(5):1039-47. doi: 10.1038/mt.2014.15. Epub 2014 Jan 30. Mol Ther. 2014. PMID: 24476798 Free PMC article.
Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates.
Pierantoni A, Esposito ML, Ammendola V, Napolitano F, Grazioli F, Abbate A, Del Sorbo M, Siani L, D'Alise AM, Taglioni A, Perretta G, Siccardi A, Soprana E, Panigada M, Thom M, Scarselli E, Folgori A, Colloca S, Taylor G, Cortese R, Nicosia A, Capone S, Vitelli A. Pierantoni A, et al. Among authors: folgori a. Mol Ther Methods Clin Dev. 2015 May 20;2:15018. doi: 10.1038/mtm.2015.18. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26015988 Free PMC article.
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.
D'Alise AM, Leoni G, Cotugno G, Troise F, Langone F, Fichera I, De Lucia M, Avalle L, Vitale R, Leuzzi A, Bignone V, Di Matteo E, Tucci FG, Poli V, Lahm A, Catanese MT, Folgori A, Colloca S, Nicosia A, Scarselli E. D'Alise AM, et al. Among authors: folgori a. Nat Commun. 2019 Jun 19;10(1):2688. doi: 10.1038/s41467-019-10594-2. Nat Commun. 2019. PMID: 31217437 Free PMC article.
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
Leoni G, D'Alise AM, Cotugno G, Langone F, Garzia I, De Lucia M, Fichera I, Vitale R, Bignone V, Tucci FG, Mori F, Leuzzi A, Di Matteo E, Troise F, Abbate A, Merone R, Ruzza V, Diodoro MG, Yadav M, Gordon-Alonso M, Vanhaver C, Panigada M, Soprana E, Siccardi A, Folgori A, Colloca S, van der Bruggen P, Nicosia A, Lahm A, Catanese MT, Scarselli E. Leoni G, et al. Among authors: folgori a. Cancer Res. 2020 Sep 15;80(18):3972-3982. doi: 10.1158/0008-5472.CAN-20-1072. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690723
New viral vectors for infectious diseases and cancer.
Sasso E, D'Alise AM, Zambrano N, Scarselli E, Folgori A, Nicosia A. Sasso E, et al. Among authors: folgori a. Semin Immunol. 2020 Aug;50:101430. doi: 10.1016/j.smim.2020.101430. Epub 2020 Nov 29. Semin Immunol. 2020. PMID: 33262065 Free article. Review.
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans.
Esposito I, Cicconi P, D'Alise AM, Brown A, Esposito M, Swadling L, Holst PJ, Bassi MR, Stornaiuolo M, Mori F, Vassilev V, Li W, Donnison T, Gentile C, Turner B, von Delft A, Del Sorbo M, Barra F, Contino AM, Abbate A, Novellino E, Thomsen AR, Christensen JP, Lahm A, Grazioli F, Ammendola V, Siani L, Colloca S, Klenerman P, Nicosia A, Dorrell L, Folgori A, Capone S, Barnes E; PEACHI Consortium. Esposito I, et al. Among authors: folgori a. Sci Transl Med. 2020 Jun 17;12(548):eaaz7715. doi: 10.1126/scitranslmed.aaz7715. Sci Transl Med. 2020. PMID: 32554708 Free PMC article.
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults.
Green CA, Scarselli E, Sande CJ, Thompson AJ, de Lara CM, Taylor KS, Haworth K, Del Sorbo M, Angus B, Siani L, Di Marco S, Traboni C, Folgori A, Colloca S, Capone S, Vitelli A, Cortese R, Klenerman P, Nicosia A, Pollard AJ. Green CA, et al. Among authors: folgori a. Sci Transl Med. 2015 Aug 12;7(300):300ra126. doi: 10.1126/scitranslmed.aac5745. Sci Transl Med. 2015. PMID: 26268313 Free PMC article. Clinical Trial.
90 results