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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, Gould J, Davis JF, Tubelli AA, Asiedu JK, Lahr DL, Hirschman JE, Liu Z, Donahue M, Julian B, Khan M, Wadden D, Smith IC, Lam D, Liberzon A, Toder C, Bagul M, Orzechowski M, Enache OM, Piccioni F, Johnson SA, Lyons NJ, Berger AH, Shamji AF, Brooks AN, Vrcic A, Flynn C, Rosains J, Takeda DY, Hu R, Davison D, Lamb J, Ardlie K, Hogstrom L, Greenside P, Gray NS, Clemons PA, Silver S, Wu X, Zhao WN, Read-Button W, Wu X, Haggarty SJ, Ronco LV, Boehm JS, Schreiber SL, Doench JG, Bittker JA, Root DE, Wong B, Golub TR. Subramanian A, et al. Among authors: flynn c. Cell. 2017 Nov 30;171(6):1437-1452.e17. doi: 10.1016/j.cell.2017.10.049. Cell. 2017. PMID: 29195078 Free PMC article.
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice.
Cottrell CA, Hu X, Lee JH, Skog P, Luo S, Flynn CT, McKenney KR, Hurtado J, Kalyuzhniy O, Liguori A, Willis JR, Landais E, Raemisch S, Chen X, Baboo S, Himansu S, Diedrich JK, Duan H, Cheng C, Schiffner T, Bader DLV, Kulp DW, Tingle R, Georgeson E, Eskandarzadeh S, Alavi N, Lu D, Sincomb T, Kubitz M, Mullen TM, Yates JR 3rd, Paulson JC, Mascola JR, Alt FW, Briney B, Sok D, Schief WR. Cottrell CA, et al. Among authors: flynn ct. Sci Transl Med. 2024 May 22:eadn0223. doi: 10.1126/scitranslmed.adn0223. Online ahead of print. Sci Transl Med. 2024. PMID: 38753806
The emergence of nitazenes on the Irish heroin market and national preparation for possible future outbreaks.
Killeen N, Lakes R, Webster M, Killoran S, McNamara S, Kavanagh P, Eagleton M, McCormack S, Micheau E, Moughty A, O'Donnell C, O'Reilly M, Doyle G, O'Rourke S, Downing S, Flynn C, Keenan E. Killeen N, et al. Among authors: flynn c. Addiction. 2024 May 8. doi: 10.1111/add.16525. Online ahead of print. Addiction. 2024. PMID: 38720174 No abstract available.
The transcription factor ZNF469 regulates collagen production in liver fibrosis.
Steinhauser S, Estoppey D, Buehler DP, Xiong Y, Pizzato N, Rietsch A, Wu F, Leroy N, Wunderlin T, Claerr I, Tropberger P, Müller M, Davison LM, Sheng Q, Bergling S, Wild S, Moulin P, Liang J, English WJ, Williams B, Knehr J, Altorfer M, Reyes A, Mickanin C, Hoepfner D, Nigsch F, Frederiksen M, Flynn CR, Fodor BD, Brown JD, Kolter C. Steinhauser S, et al. Among authors: flynn cr. bioRxiv [Preprint]. 2024 Apr 25:2024.04.25.591188. doi: 10.1101/2024.04.25.591188. bioRxiv. 2024. PMID: 38712281 Free PMC article. Preprint.
Specific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines-an exploratory sub-study of the BRACE trial.
Messina NL, Germano S, McElroy R, Bonnici R, Grubor-Bauk B, Lynn DJ, McDonald E, Nicholson S, Perrett KP, Pittet LF, Rudraraju R, Stevens NE, Subbarao K, Curtis N; BRACE trial. Messina NL, et al. EBioMedicine. 2024 May;103:105100. doi: 10.1016/j.ebiom.2024.105100. Epub 2024 Apr 24. EBioMedicine. 2024. PMID: 38663355 Free PMC article.
733 results